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  • ISSN: 2333-6692
    Volume 7, Issue 1
    Review Article
    Akanksha Singh* and Rita Singh Raghuwanshi
    Vitamin D plays an important role in bone growth and maintenance by enhancing intestinal absorption of calcium and influencing bone metabolism in women and improves biochemical markers for Osteoporosis. Vitamin D deficiency in adults can exacerbate osteopenia and osteoporosis, cause osteomalacia and muscle weakness, and increase the risk of fracture. Osteoporosis is a disorder having characteristic features of low bone mass and structural degeneration, promoting the development of brittleness of the bones and increasing the risk of fractures of the bones of pelvis, vertebral column and wrist. Osteoporosis is estimated to affect 200 million women worldwide - approximately one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and two-third of women aged 90. Since bone loss occurs without symptoms, osteoporosis is often considered a ‘silent disease’. Menopausal is commonly defined by the state of the uterus and the absence of menstrual flow or "periods," but it can instead be more accurately defined as the permanent cessation of the primary functions of the ovaries. A drop in estrogens production after menopause results in increased bone reasorption, leads tothe risk of osteoporosis during menopause and decreased calcium absorptionPostmenopausal women have a higher risk of falling or fracture when they do not maintain serum 25-hydroxyvitamin D levels higher than 30 ng/mL.
    Case Report
    Semin Fenkci, Nagehan Yalcin, Ergin Sagdas, Senay Topsakal, and Guzin F. Yaylali
    Pheochromocytoma [PHEO] and Cushing syndrome [CS] may sometimes coexist and very rarely originate from the same adrenal gland. There were 12 cases in the literature in which corticomedullary involvement has been reported. A few cases of primary aldosteronism coexisting with Pheochromocytomahave been reported so far. Also there is very little information about pheochromocytoma associated with Cushing’s syndrome. Cushing’s syndrome secondary to ectopic adrenocorticotropic hormone [ACTH] secretion has been frequently reported nowadays. Our literature search revealed no previous reports of a patient with PHEO and CS originating from the same adrenal gland and coexistent with acromegaly.
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