Early Online
Volume 5, Issue 1
Review Article
John Torma, Brian Marples, Sarah A. Krueger, Katie Buelow and George D. Wilson*
Small animal imaging is a critical component of modern cancer research that bridges the gap between experimental and clinical studies. Setting up and operating a small animal PET research facility is a complex undertaking with unique challenges governed by radiation safety and animal care regulations. Although each institution will face its own local concerns and restrictions, the key components that go into the planning and operation of a small animal PET imaging facility are described. The main elements that are required include equipment, space, radiation safety, animal care, record keeping and technical aspects of injections and image acquisition. Finally, representative images are presented from different experimental studies.
Research Article
Shivanand S.Gornale*, Pooja U.Patravali and Prakash S.Hiremath
Osteoarthritis is a chronic degenerative joint disease called as “Wear and Tear” arthritis that results in progressive erosion of articular cartilage and results in disability. Earlier work reveals that various segmentation and classification methods have been implemented for the assessment of the disease but due to unavailability of standard benchmark database the comparative analysis of individual methods is still missing. In this paper, we present a comprehensive dataset of digital Knee X-ray images complaint with DICOM (Digital Imaging and Communications in Medicine) standards with manual annotations made by two different medical experts as per Kellgren and Lawrence grading system. The paper divulge the study of various state of art methods that includes region based methods, density based methods and statistical evaluation measures for early assessment of ailment and severity level as per KL grading system against this dataset.
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