Recent Articles
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November 03, 2023 Research ArticleAbstract Aim: In this study, we sought to verify a mathematical model, ME = 0.87 * MM + 4, by performing tests on a sample of individuals with known chordae length by echographic measurement. Patients & methods: This report presents a retrospective analysis .....
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September 09, 2023 Research ArticleShort-Term Exposure to Coarse Particles and Dyslipidemia Risk in Chengdu, China: A Time-Series StudyAbstract Objectives: Dyslipidemia, as a major risk factor for atherosclerotic cardiovascular disease (CVD), contributed to a large number of deaths. Ambient air pollution was recognized as a significant risk factor for dyslipidemia. We designed the study to e.....
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July 31, 2023 Short CommunicationAbstract Objective: This study was devoted to clustering the growth of research outputs among the top-ranking 20 countries in the field of public, environmental and occupational health. Method: This is a longitudinal bibliometric study that uses SCImago Journ.....
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November 11, 2020 Original ResearchAbstract Delayed treatment bears no good results other than shielding financial loss temporarily. But the long-term effects can be dangerous, both for recovery and budgetary burden. Still more than 72% of Bangladeshi workers take the risk of not rushing to he.....
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August 08, 2020 Review ArticleAbstract Current statistical procedures implemented in statistical software packages for the aggregation of diagnostic test accuracy data include hierarchical regression and the bivariate random-effects meta-analysis model. However, these models do not report.....
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August 07, 2020 Research ArticleAbstract Background: Time to death predictors of heart failure not yet clear and the prevalence became increases time to time in the world. Even though there was an improvement in management of heart failure patients, still it needs more attention, especially.....
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July 10, 2020 CommentaryAbstract In 1967 Frederic Lord published a two page paper on weight changes over time by two groups. He asked what inferences should be drawn from the data shown. A scientist would surely conclude that the individuals in both groups were fluctuating in weight.....
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June 05, 2020 Research ArticleAbstract Obesity is identified as a major global health problem. Along with measuring Body Mass Index (BMI), the most common metric for defining weight status, health related quality of life (HRQol) has been accepted as a routine method to evaluate how body w.....
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March 23, 2020 Review ArticleAbstract Despite the fact that a large number of candidate biomarkers have been identified by biologists during the last decades, very few of these have made it all the way to clinical practice. One of the reasons for this is lack of proper validation on a le.....
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February 24, 2020 Research ArticleAbstract A cellular function emerges from a collective action of a large number of proteins interacting and affecting each other. A major challenge in the recognition of protein interaction networks is the cell-to-cell heterogeneity within a sample. This hete.....
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April 18, 2018 Short CommunicationAbstract Memory of food products has been claimed to be more important than the product itself in shaping consumer food choices. For this reason, understanding how to create memorable products for consumers becomes a key aspect to achieve success in the marke.....
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November 16, 2017 Research ArticleAbstract Hidden Markov models (HMMs) are well known powerful and flexible statistical methods for modeling one dimensional time series data. They are used when the vector of observation and hidden states are processed. Sometimes, a matrix of data (spatial str.....
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October 20, 2017 Short CommunicationAbstract Statistical noise is usually a main concern in collecting data. Technical malfunction of devices or asynchronous data collection could easily lead to noise appearance. In this paper, we provide some methods for handling noise through the development .....
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June 09, 2017 Short CommunicationAbstract The Microbial Resource Research Infrastructure (MIRRI) stresses the importance of access to microbial data as well as to high quality microorganisms in the execution of sound science and innovative research and development. MIRRI’s mission is to re.....
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December 05, 2016 EditorialAbstract The use of (generalized) linear regression is ubiquitous in genetic association studies of complex phenotypes. In this area, homoscedasticity is often assumed, namely, the variances of modelling errors are assumed to be invariant with respect .....
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November 06, 2015 Review ArticleAbstract The comet assay is a simple, rapid and sensitive tool for direct visualization of DNA damage in individual cells. This assay is commonly applied in regulatory genotoxicological studies and environmental monitoring. It is well known that data generate.....
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June 05, 2015 Review ArticleAbstract Reports on misuse of statistical methods in biological research are increasing at alarming rate. These reports highlight the irreproducibility of results as the major problem of laboratory experiments in many scientific communications. The basic prob.....
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December 29, 2013 Short CommunicationAbstract Incorporating both Bayesian and frequentist methods in the same model the hybrid Bayesian statistical inference possesses some advantages over either of the methods used individually. It has been increasingly applied to biomedical research including .....
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April 22, 2015 Review ArticleAbstract The number of co-infections with a pathogen (multiplicity of infection or MOI) is a relevant parameter in epidemiology. It relates to transmission intensity and can be built into a metric in the context of disease control and prevention. Here, a maxi.....
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February 03, 2015 Research ArticleAbstract Conventional measurements of systolic cardiac function and cardiac output may be influenced by loading conditions. The presence of extra-cardiac shunts in the transitional circulation limits the application of such measures in a neonatal population. .....
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March 09, 2015 Short CommunicationAbstract Dengue represents a serious public health problem in the world, and human global travel has contributed to new outbreaks or epidemics in propitious places around the world. Mathematical models that employ climatic information and associated social va.....
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November 28, 2014 Research ArticleAbstract For the data on unaided distance vision of women in Britain, this paper proposes new statistical models which give easy and simple interpretation, and gives decompositions of existing models which are useful for investigating the data in more detail......
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April 09, 2015 Short CommunicationAbstract Foot and mouth disease (FMD) is one of the most contagious diseases of animal livestock in the world in terms of economic impact. FMD is endemic in the dry zone of Sri Lanka and considered to be a common disease among cattle and buffaloes in this are.....
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March 26, 2015 Review ArticleAbstract Background: Pharmaceutical companies, regulatory agencies, or other government agencies conduct safety signal detection as one of the ways for mitigating the possible risks due to medical products. The safety signal is defined as information that ari.....
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March 09, 2015 Short CommunicationAbstract A bootstrap-based extension of Akaike information criterion (AIC), termed extended information criterion (EIC), is newly applied to determine the co-integration rank. Simulation results suggest that in terms of correct model selection, EIC considerab.....
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December 06, 2014 Research ArticleAbstract In public health surveillance, several methods have been proposed to identify regions with excess numbers of diseased individuals. Often the methods are demonstrated on proprietary data and power investigations are seldom included. This paper aims to.....
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December 01, 2014 Review ArticleAbstract The microarray and the deep sequencing have become major technologies for gene function discovery and transcriptome regulatory mechanism exploration. The differential gene expression analysis takes an important role for disclosing biological function.....
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June 02, 2014 Review ArticleAbstract Differential biomarkers detection from a genomic study poses big challenges for statistical analysis with a large number of markers and a small number of samples. Due to the presence of a large number of markers, Bayesian hierarchical approaches are .....
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June 06, 2014 Review ArticleAbstract In recent years, as more and more innovative drug products are going off patents, the search for new medicines such as botanical drug products that can treat critical and/or life-threatening diseases has become the center of attention of many pharmac.....
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April 20, 2014 Research ArticleAbstract Longitudinal data arise frequently in medical studies and it often happens in longitudinal studies that collected data are observed with the following typical features. (i) Individuals may follow a heterogeneous population (rather than homogeneous po.....
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October 24, 2013 Review ArticleAbstract Variable selection in the context of a linear model or a linear mixed model is a fundamental but often contentious part in applied statistical model building. However, very little on the topic is available in statistical literature. In the current ar.....
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October 24, 2013 Letter to the EditorAbstract Besides three books - Multivariate Analysis, A course in Linear Models and Growth Curves, my research contributions to Statistics and Biostatistics are in the following areas: (a) Experimental Designs and Linear Models, (b) Multivariate Analysis and .....
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October 31, 2013 EditorialAbstract (This year, statisticians worldwide are celebrating the International Year of Statistics 2013. Statistics, as a unique subject in data science, has grown enormously during the past fifty years, in particular the most recent twenty years when informat.....
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October 09, 2013 Research ArticleAbstract Longitudinal studies typically suffer from incompleteness of data. Especially in studies of the older persons, attrition is a major problem since participants are likely to die during the study or are too frail to participate in follow-up examination.....
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August 29, 2013 Research ArticleAbstract In this note we provide a straightforward approach for calculation of the per hypothesis error rate in a multiple testing framework given a general stepwise testing procedure. This approach is based on a general result due to coined Steck’s determi.....
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August 21, 2013 EditorialAbstract I must confess that I’m an ardent gardener. Let’s think about it, to plant something is really simple, the sun is a free gift from God, there are plenty of rich soils in the US, and water is plenty and inexpensive too. So I started to grow some v.....
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June 28, 2013 Research ArticleAbstract Multilevel latent class analysis (MLCA) has been built into a few statistical software to analyze nested data that do not satisfy the conditional independence assumption of simple Latent class analysis (LCA). Multilevel latent class regression (MLCR).....
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June 25, 2013 Review ArticleAbstract This manuscript reviews important work about the B-spline-based sieve maximum likelihood estimation in survival analysis including studies for nonparametric and semiparametric problems. It also discusses some advantages of spline-based sieve estimati.....
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June 19, 2013 Research ArticleAbstract In the design of a randomized clinical trial with one pre and multiple post randomized assessments of the outcome variable, one needs to account for the repeated measures in determining the appropriate sample size. Unfortunately, one seldom has a go.....
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June 20, 2013 Research ArticleAbstract In observational studies, marginal structural models are often used to adjust for confounding. When predicting propensity scores, some investigators may want to apply a logistic regression model with a random coefficient to take account of residual c.....