Recent Articles
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March 29, 2024 Research ArticleAbstract Nitraria tangutorum Bobrov is a berry shrub with white flowers and red fruits, which grows in the deserts in the Tibetan Plateau, Mongolia, and western China. Its fruit N. tangutorum Fruit (NTF) contains various bioactive compounds, with anti-fatig.....
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February 08, 2024 Original ResearchAbstract Soil salinity is distinguished in primary and a secondary salinity. The primary one is a consequence of natural processes of rock disintegration that release soluble salts, such as chlorides of sodium, calcium and magnesium, sulphates and carbonates .....
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September 20, 2020 Review ArticleAbstract The recent FDA approval of CAR-T cell therapy products has generated much excitement in the field, but also met with some reservation due to their hefty price tags. Because cell therapy products are living tissues that need to be individualized to t.....
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July 07, 2018 Review ArticleAbstract Alpha amylase (?-amylase) (EC 3.2.1.1) is an endo-amylolytic enzyme that plays an important role in seed germination in wheat. However, excessive ?-amylase in post-harvest wheat grains has a negative effect on wheat yield and end-products quality......
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May 31, 2018 Research ArticleAbstract Cytoplasmic male sterility system has been widely been used for increasing sorghum yield through heterosis exploitation. To effectively use male–sterility inducing cytoplasm, it is necessary to identify restorers and lines that are suitable for c.....
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May 16, 2018 Research ArticleAbstract The development of successful improved sorghum varieties for the Western Africa requires the incorporation of farmer’s perceptions and desires into the end product. Failure to do this in the past probably explains the low rate of adoption of impr.....
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January 30, 2018 Research ArticleAbstract Jordanian Dolomite was investigated as a heterogeneous catalyst in biodiesel production from Jatropha oil. In order to study the thermal activation process of dolomite, dolomite samples were thermally treated for two hours at 100, 200, 300, 400 500.....
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January 30, 2018 Review ArticleAbstract Microbial biofuel production using renewable resources is an important alternative to conventional petroleum-based fuels. In this respect, conversion of the cellulosic biomass as the renewable resource to simple sugars and biofuels is the main stra.....
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January 02, 2017 Short CommunicationAbstract Introduction/Objectives: The deleterious health effects of tobacco smoking are now widely recognized and documented. High-resolution 1 H NMR analysis of human saliva provides a high level of valuable molecular information regarding the nature and le.....
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October 16, 2017 Research ArticleAbstract The in vitro and in vivo antibacterial activity of marine alga, Turbinaria ornata against Pseudomonas aeruginosa on Macrobrachium rosenbergii was studied. The hexanic, acetonic and methanolic extracts of T. ornata were subjected to in vitro study, w.....
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July 31, 2017 Review ArticleAbstract Development of effective anti-cancer therapies continues to be a challenge due to genetic instability that promotes intra-tumoral molecular heterogeneity and subsequent adaptation to therapy. In this review, we briefly discuss the history of the p5.....
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June 30, 2017 Review ArticleAbstract As an important part of precision medicine, liquid biopsy attracts more and more attention of scholars and clinicians. It refers to the real-time monitoring of the dynamic alterations of tumor by detecting circulating tumor cells (CTCs), circulating .....
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May 10, 2017 Short CommunicationAbstract Myostatin, a negative regulator of skeletal muscle growth, is also expressed in cardiac muscle; however its function in this tissue is poorly understood. In this study, the CRISPR/Cas9 system was used to inactivate mstn in zebrafish. Microinjection.....
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March 28, 2017 Short Communication
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March 28, 2017 Short CommunicationAbstract Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. The mitochondria dysfunction has long been appreciated in PD pathogenesis and can be the common pathological pathway contributing to dopaminergic (DA) neuron d.....
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March 22, 2017 Short CommunicationAbstract MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally control mRNA abundance and thus critically regulate cellular phenotypes. Inter alia, efforts were made to engineer Chinese hamster ovary (CHO) cells which represent the most fre.....
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March 22, 2017 Short CommunicationAbstract Bioreactor design is an integral part of bioprocess intensification. The sole aim of process design is to identify the thrust areas and improve the production of the desired metabolite. Complex secondary metabolites like antibiotics are of great impo.....
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December 20, 2016 Mini ReviewAbstract C. elegans has become a versatile model organism because of various advantages, such as being a small-sized non-parasitic worm with a transparent body and a short life cycle, along with the capacity to conduct in vivo live worm imaging, genetic amen.....
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December 09, 2016 Mini ReviewAbstract Annotation of microRNAs (miRNAs) is a prerequisite to the study of their functional analysis at the genome scale. The first list of criteria published for miRNA annotation was established in 2003 by the group of Thomas Tuschl and since then, a large .....
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December 01, 2016 Mini ReviewAbstract Micro-RNAs (miRNAs) are endogenous, evolutionarily conserved, non-coding, RNAs of about 20-25 nucleotides in length. They control cell fate via cell proliferation, differentiation, apoptosis and stress response. They regulate gene expression by pri.....
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November 18, 2016 Short CommunicationAbstract The occurrence of harmful cyanobacterial blooms in surface waters is often associated with the production of a variety of cyanotoxins, which are able to target specific human organs where they badly act. During this project, as a monitoring purpose, .....
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November 18, 2016 Review ArticleAbstract MicroRNAs are a large family of short non-coding RNA molecules involved in the regulation of gene expression. MIRN21 gene residing on chromosome 17 is linked to cancer initiation, progression and therapeutic response. The mature miRNA is 22 nucleo.....
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November 01, 2016 Research ArticleAbstract AmyJ33 is an ?-amylase from Bacillus amyloliquefaciens JJC33M is not calcium dependent and is active on native and raw starch. In this work, a deeper biochemical and kinetic characterization was made. AmyJ33 presented an optimum pH and temperature at.....
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October 13, 2016 Short NoteAbstract Pioneering preclinical studies have demonstrated that cardiomyocytes generated from pluripotent stem cells (PSC-CMs) hold tremendous potential for the treatment of tissue loss and insufficiency (such as HF and MI) that result from heart disease. PSCs.....
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October 13, 2016 Research ArticleAbstract Whilst breast cancer (BC) management continues to improve, the requirement of novel assays to support the accuracy of HER2 clinical diagnosis remains. Investigation of the potential for miRNAs, recently identified biomarkers of both predictive and pr.....
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October 06, 2016 Research ArticleAbstract The objective of this study was to determine the effect of colostrum on microbial populations of yogurt and kefir. For this purpose, raw bovine colostrum is freeze-dried and added to yogurt and kefir on 8% and 16% (w/w; colostrum/product) dilutions. .....
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October 06, 2016 Short CommunicationAbstract Here we describe the screening and characterization of a lignin-degrading bacterium from an environmental sample. The bacterium was isolated from leaf soil and identified as Pseudomonas sp. strain CCA1 based on 16S rRNA gene sequencing. Although iden.....
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October 04, 2016 Mini ReviewAbstract Early diagnosis and monitoring of treatment are essential for the efficient management of patients. In this regard, significant efforts have been made to find informative, blood (and other biological fluids) -based biomarkers. Thanks to their innate .....
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September 20, 2016 Review ArticleAbstract Mechanical forces are known to play a role in cell behavior and adaptation within their environment. In recent years, special attention has been paid to how these forces interact with various stem cell sources to direct stem cell differentiation. E.....
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September 13, 2016 Short CommunicationAbstract Rapid advances in genome editing technology allow the targeted genes to be modified both in vitro and in vivo. In this short communication, we will summarize the development and progress in genome editing techniques and highlight their application in.....
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August 22, 2016 Mini ReviewAbstract In this paper we show, in silico, the role of miRNAs in the post-transcriptional regulation of the onco suppressor gene PTEN by means of a (stochastic) competitive model including interactions with miRNAs and other concurrent genes. The model also co.....
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July 28, 2016 Review ArticleAbstract The use of stem cells in clinical trials started several years ago for regenerative-based therapies or for the treatment of tumours. After brain injuries or neurodegenerative diseases, neural stem cells represent a promising strategy to repair the .....
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July 22, 2016 Mini ReviewAbstract While two-dimensional (2D) cell culture is still a dominant method in many biological studies, three-dimensional (3D) culture systems have gained significant attention in stem cell, cancer research, and tissue engineering. For the past few years, num.....
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July 08, 2016 Short CommunicationAbstract The differentiation of human Bone-Marrow Mesenchymal Stem/Stromal Cells (hBM-MSCs) is dependent on exposure to biophysical and biochemical stimuli that favor early and rapid activation of the in vivo tissue repair process [1]. Exposure to exogenous s.....
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July 08, 2016 Review ArticleAbstract This paper will explore mainly donated by brain dead liver donors (DBD). Brain death could induce much physiological and metabolic change in tissues, which is associated with hemodynamic instability and the increase of inflammatory mediators. Injury .....
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June 24, 2016 Short CommunicationAbstract Filamentous fungi are very important cellulose-degrading microorganisms in nature. The main cellulolytic fungi are Aspergillus, Trichoderma, Penicillium, Acremonium. Cellulases have played an important role in many industrial processes as fiber texti.....
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June 24, 2016 Mini ReviewAbstract Probiotics food products contain live microorganisms, which contribute to its preservation, taste, texture and aroma, as well as providing the balance of the natural microbiota of those who consume it, often improving the absorption of nutrients.
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June 17, 2016 Review ArticleAbstract Bone grafting have been used to treat nonunion, union and acute fractures. Autologous cancellous bone grafts are still the most effective graft material for stimulating bone repair since they present osteoconduction, osteoinduction and osteogenic cap.....
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May 31, 2016 Short CommunicationAbstract The aim of our study was to develop a model for farm monitoring, to be used in the case of the suspected presence of C. burnetii. Such a model could also be used to identify possible threats to human health. Thus, a C. Burnetii positive sheep farm w.....
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February 15, 2016 Review ArticleAbstract Kefir grains are multi-species natural starter culture and widely used in fermented dairy products. Kefir grains contain many bacterial species already known for their probiotic properties. Our review provides an overview of kefir grains’ microbiol.....
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May 15, 2016 Review ArticleAbstract Background and Aim: Although reactive oxygen species (ROS) are often attributed to pathological outcomes, they do function as important modulators of many cellular processes involved in homeostasis and cell survival. Hyperbaric oxygen therapy (HBOT) .....
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April 18, 2016 Review ArticleAbstract Cell-based therapies have been increasingly explored as a potential alternative treatment method of corneal endothelial dysfunction. Up to date, researchers have mainly dedicated enormous efforts to establishing fundamental techniques for culture and.....
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June 13, 2016 Short CommunicationAbstract Selected or biologically (gene-) engineered substances from the silkworm can be produced in standardized form all year round by automated bioreactors that are based on genomically stable, easy and indefinitely long with 100% effectiveness reproducibl.....
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December 29, 2014 Review ArticleAbstract The paper informs about the specific shifts in metal-ligand homeostasis (MLH) of epidermic cells (hair) in Chernobyl accident liquidators, which are viewed by the authors as biomarkers of oxidative/nitrosative stress. The detected (by EPR-analysis) r.....
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March 13, 2016 Short CommunicationAbstract Selected or biologically (gene-) engineered substances from the silkworm can be produced in standardized form all year round by automated bioreactors that are based on genomically stable, easy and indefinitely long with 100% effectiveness reproducibl.....
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November 26, 2014 Research ArticleAbstract Indiscriminate location of petrol filling stations is of public health concern, as these filling stations are located around residential and agricultural areas. This study assessed the mutagenicity of simulated leachate from soil collected from pet.....
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November 05, 2014 Short CommunicationAbstract Novel biocompatible poly(ethylene glycol) (PEG)-stabilized CoO nanoparticles have been synthesized. The particles exhibited a near-infrared laser-based photoacoustic signal that was 11 times stronger than that of our previously developed gadolinium o.....
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August 09, 2014 Research ArticleAbstract Purpose: The goal of this study was the clinical evaluation of the neuroprotective properties of a dietary supplementation of forskolin, rutin and vitamins B1 and B2 on retinal ganglion cell activity. To this purpose, we focused both on IOP and the P.....
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May 21, 2014 Review ArticleAbstract Heavy metal contamination is potentially a significant environmental issue and certainly a major health concern in many parts of the world, primarily due to various anthropogenic activities. Amid various eco-friendly remediation processes, bioremedia.....
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January 07, 2013 Case ReportAbstract Influenza virus infection-induced autoimmune hemolytic anemia (AIHA) is extremely rare. This report describes a case of AIHA that was induced by type A influenza infection in a patient with alcoholic liver cirrhosis. In addition, a review of the medi.....
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November 11, 2013 Mini ReviewAbstract The involvement of hydrogen sulfide (H2S) in a number of cellular signal transduction pathways has triggered great interest in the development of selective and sensitive detection methods for H2S. This mini-review summarizes three current strategies .....
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October 03, 2013 Research ArticleAbstract Gene regulation is central to the biological processes of differentiation, morphogenesis, and the creation of diversity of cell types. The identification of gene regulatory elements is thus essential for the understanding of the molecular mechanism u.....
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September 19, 2013 Review ArticleAbstract Photoreceptor cells are highly specialized cells that convert light energy into electric signals. Ten percent of their outer segment membranes (approximately 77 cm2 of membrane) are renewed every day. Therefore, photoreceptor cells must possess an ex.....
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September 13, 2013 Research ArticleAbstract Climate change, limited fossil resources and steady population growth drive industrial development of sustainable biomass based processes for production of fuels, platform and specialty chemicals. In this context phototrophic microalgae cultivation p.....
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September 04, 2013 Short Communication
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September 02, 2013 Short Communication
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September 02, 2013 Editorial
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September 04, 2013 Research ArticleAbstract Climate change and dwindling fossil resources drive industrial developments of biomass based processes for chemical and fuel applications. Butanol is poised to be a next generation renewable building block due to its improved energy content and hydro.....
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September 04, 2013 Review ArticleAbstract In terms of production capacities and economical relevance biodiesel is the most important transportation biofuel. In contrast to other biofuel options, biodiesel processes have recently experienced little technology development. The industrial stand.....
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September 02, 2013 Editorial
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August 26, 2013 EditorialAbstract Peptidyl-tRNA hydrolases (Pths) are essential enzymes found in bacteria, archaea, and eukaryotes. Pths cleave the peptide:tRNA ester bond of peptidyl-tRNAs generated from premature termination of protein synthesis and the expression of short ORFs o.....
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August 21, 2013 Editorial
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August 16, 2013 Editorial
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August 16, 2013 Review ArticleAbstract Tyrosine O sulfation is a post translational modification (PTM) originally discovered by Bettelheim in 1954 in the bovine protein fibrinogen. Currently, this PTM is found only in secreted and transmembrane proteins of higher eukaryotes. This article .....
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July 31, 2013 Review ArticleAbstract Natural compounds have been discovered to be effective in many disease treatments. Among these compounds are epigallocatechin-3-gallate (EGCG) and epicatechin-3-gallate (ECG), two abundant polyphenolic catechins in green tea. They have been found to .....