AbstractC. elegans has become a versatile model organism because of various advantages, such as being a small-sized non-parasitic worm with a transparent body and a short life cycle, along with the capacity to conduct in vivo live worm imaging, genetic amena.....
AbstractAnnotation of microRNAs (miRNAs) is a prerequisite to the study of their functional analysis at the genome scale. The first list of criteria published for miRNA annotation was established in 2003 by the group of Thomas Tuschl and since then, a large .....
AbstractMicro-RNAs (miRNAs) are endogenous, evolutionarily conserved, non-coding, RNAs of about 20-25 nucleotides in length. They control cell fate via cell proliferation, differentiation, apoptosis and stress response. They regulate gene expression by prima.....
AbstractThe occurrence of harmful cyanobacterial blooms in surface waters is often associated with the production of a variety of cyanotoxins, which are able to target specific human organs where they badly act. During this project, as a monitoring purpose, .....
AbstractMicroRNAs are a large family of short non-coding RNA molecules involved in the regulation of gene expression. MIRN21 gene residing on chromosome 17 is linked to cancer initiation,
progression and therapeutic response.
The mature miRNA is 22 nucleo.....
AbstractAmyJ33 is an ?-amylase from Bacillus amyloliquefaciens JJC33M is not calcium dependent and is active on native and raw starch. In this work, a deeper biochemical and kinetic characterization was made. AmyJ33 presented an optimum pH and temperature at.....
AbstractPioneering preclinical studies have demonstrated that cardiomyocytes generated from pluripotent stem cells (PSC-CMs) hold tremendous potential for the treatment of tissue loss and insufficiency (such as HF and MI) that result from heart disease. PSCs.....
AbstractWhilst breast cancer (BC) management continues to improve, the requirement of novel assays to support the accuracy of HER2 clinical diagnosis remains. Investigation of the potential for miRNAs, recently identified biomarkers of both predictive and pr.....
AbstractThe objective of this study was to determine the effect of colostrum on microbial populations of yogurt and kefir. For this purpose, raw bovine colostrum is freeze-dried and added to yogurt and kefir on 8% and 16% (w/w; colostrum/product) dilutions. .....
AbstractHere we describe the screening and characterization of a lignin-degrading bacterium from an environmental sample. The bacterium was isolated from leaf soil and identified as Pseudomonas sp. strain CCA1 based on 16S rRNA gene sequencing. Although iden.....
AbstractEarly diagnosis and monitoring of treatment are essential for the efficient management of patients. In this regard, significant efforts have been made to find informative, blood (and other biological fluids) -basedbiomarkers. Thanks to their innate c.....
AbstractMechanical forces are known to play a role in cell behavior and adaptation within their environment. In recent years, special attention has been paid to how these forces interact with various stem cell sources to direct stem cell differentiation. Emb.....
AbstractRapid advances in genome editing technology allow the targeted genes to be modified both in vitro and in vivo. In this short communication, we will summarize the development and progress in genome editing techniques and highlight their application in.....
AbstractIn this paper we show, in silico, the role of miRNAs in the post-transcriptional regulation of the onco suppressor gene PTEN by means of a (stochastic) competitive model including interactions with miRNAs and other concurrent genes. The model also co.....
AbstractThe use of stem cells in clinical trials started several years ago for regenerativebased therapies or for the treatment of tumours. After brain injuries or neurodegenerative diseases, neural stem cells represent a promising strategy to repair the af.....
AbstractWhile two-dimensional (2D) cell culture is still a dominant method in many biological studies, three-dimensional (3D) culture systems have gained significant attention in stem cell, cancer research, and tissue engineering. For the past few years, num.....
AbstractThe differentiation of human Bone-Marrow Mesenchymal Stem/Stromal Cells (hBM-MSCs) is dependent on exposure to biophysical and biochemical stimuli that favor early and rapid activation of the in vivo tissue repair process [1]. Exposure to exogenous s.....
AbstractThis paper will explore mainly donated by brain dead liver donors (DBD). Brain death could induce much physiological and metabolic change in tissues, which is associated with hemodynamic instability and the increase of inflammatory mediators. Injury .....
AbstractFilamentous fungi are very important cellulose-degrading microorganisms in nature. The main cellulolytic fungi are Aspergillus, Trichoderma, Penicillium, Acremonium. Cellulases have played an important role in many industrial processes as fiber texti.....
AbstractProbiotics food products contain live microorganisms, which contribute to its preservation, taste, texture and aroma, as well as providing the balance of the natural microbiota of those who consume it, often improving the absorption of nutrients.
AbstractBone grafting have been used to treat nonunion, union and acute fractures. Autologous cancellous bone grafts are still the most effective graft material for stimulating bone repair since they present osteoconduction, osteoinduction and osteogenic cap.....
AbstractThe aim of our study was to develop a model for farm monitoring, to be used in the case of the suspected presence of C. burnetii. Such a model could also be used to identify possible threats to human health. Thus, a C. Burnetii positive sheep farm wa.....
AbstractKefir grains are multi-species natural starter culture and widely used in fermented dairy products. Kefir grains contain many bacterial species already known for their probiotic properties. Our review provides an overview of kefir grains’ microbiol.....
AbstractBackground and Aim: Although reactive oxygen species (ROS) are often attributed to pathological outcomes, they do function as important modulators of many cellular processes involved in homeostasis and cell survival. Hyperbaric oxygen therapy (HBOT) .....
AbstractCell-based therapies have been increasingly explored as a potential alternative treatment method of corneal endothelial dysfunction. Up to date, researchers have mainly dedicated enormous efforts to establishing fundamental techniques for culture and.....
AbstractSelected or biologically (gene-) engineered substances from the silkworm can be produced in standardized form all year round by automated bioreactors that are based on genomically stable, easy and indefinitely long with 100% effectiveness reproducibl.....