Volume 2 - Issue 3 Articles
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ArticleDecember 11, 2014 | Pages : 205 - 450Abstract Objective: This study was carried out to examine the pattern and treatment outcomes of salivary gland tumors in Nigerian patients attending Radiotherapy clinic at the University College Hospital, Ibadan. Methodology: Retrospective review of clinic.....
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ArticleDecember 11, 2014 | Pages : 205 - 450Abstract Cytogenetic abnormalities including the gain and loss of chromosomes play an important role in oncogenesis. Aberrations involving chromosome 1 are one of the most common anomalies reported among human neoplasms and have been observed in both solid.....
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ArticleDecember 03, 2014 | Pages : 205 - 450Abstract Epigenetic approach in treating different diseases has gained importance as the inhibition of the enzymes involved in epigenetic modifications can reverse the disease condition. The major epigenetic markers include DNA methylation, histone acetylat.....
Volume 2 - Issue 2 Articles
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ArticleNovember 24, 2014 | Pages : 205 - 450Abstract Primary squamous cell carcinoma of the thyroid represents less than 1% of all thyroid malignancies. Unlike other thyroid cancers, it is often fatal. We report a rare case of a male patient with primary squamous cell carcinoma of the thyroid. This p.....
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ArticleOctober 06, 2014 | Pages : 205 - 450Abstract Stem cells are differentially modulated and fated by the influence of their microenvironment, commonly known as ‘stem cell niche’. Studies of stem cell niche transformation leading to its malignancy and signaling molecules involved therein, is .....
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ArticleSeptember 22, 2014 | Pages : 205 - 450Abstract Parity (childbearing) significantly decreases a woman’s risk of breast cancer. Several factors within the mammary gland are postulated to contribute to parityinduced protection including (but not restricted to), a reduction in the number of mamm.....
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ArticleSeptember 26, 2014 | Pages : 205 - 450Abstract Patients with pancreatic adenocarcinoma face many quality of life issues. Prior to the development of the FOLFIRINOX (5-FU, irinotecan, oxaliplatin, and leucovorin) [1,2] and gemcitabine/ nab-paclitaxel [3] chemotherapeutic regimens the survival.....
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ArticleSeptember 16, 2014 | Pages : 205 - 450Abstract Cancer, especially epithelial cancer (lung, breast, colon etc.), is the most important global public health problem [1]. Understanding of the mechanism of cancer has been gaining momentum for some years on account of its high incidence and im.....
Volume 2 - Issue 1 Articles
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ArticleMay 20, 2014 | Pages : 205 - 450Abstract Pancreatic cancer is one of the deadliest human malignancies and little progress has been achieved in its treatment over the past decades. Historically, chemotherapy or radiotherapy did not provide significant survival benefit in advanced pancreati.....
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ArticleMay 15, 2014 | Pages : 205 - 450Abstract P38-regulated and activated kinase (PRAK/MAPKAPK5) is a serine/threonine kinase which lies downstream of the p38 and ERK3/4 MAP kinase pathways. PRAK plays diverse roles in the processes of cell growth, nutrient starvation response, programmed cel.....
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ArticleMarch 20, 2014 | Pages : 205 - 450Abstract Breast cancer is the most common cancer in women worldwide with around 1 in 9 women developing breast cancer during their lifetime [1,2]. In the United States of America 230,000 women were diagnosed with breast cancer in 2013 [2]. 16-20% of w.....
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ArticleMarch 20, 2014 | Pages : 205 - 450Abstract Ball valve effect is an unusual albeit life threatening phenomenon resulting in tension pneumothorax in extreme cases. We report a case of a patient with extensive stage small cell lung cancer who developed type 1 respiratory failure, during his fi.....
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ArticleJanuary 19, 2014 | Pages : 205 - 450Abstract Colorectal cancer is the 3rd most commonly diagnosed cancer within the United States and the 2nd leading cause of cancer-related deaths in the US in 2008. The survival rate for patients suffering from CRC is directly proportional to the stage of .....
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