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  • ISSN: 2333-6676
    Volume 1, Issue 1
    July-September 2013
    Editorial
    Wilbert S. Aronow*
    PAD is chronic arterial occlusive disease of the lower extremities caused by atherosclerosis. Significant independent risk factors for PAD in 467 men, mean age 80 years, and in 1,444 women, mean age 81 years, living in the community and seen in an academic geriatrics paractice were age (odds ratio = 1.05 for each 1-year increase in age in men and 1.03 for each 1-year increase in age in women); current cigarette smoking (odds ratio = 2.6 for men and 4.6 for women); systolic or diastolic hypertension (odds ratio = 2.2 for men and 2.8 for women); diabetes mellitus (odds ratio = 6.1 for men and 3.6 for women); serum high-density lipoprotein cholesterol (odds ratio = 0.95 for each 1 mg/dl increase in men and 0.97 for each 1 mg/dl increase in women); and serum low-density lipoprotein (LDL) cholesterol (odds ratio = 1.02 for each 1 mg/dl increase in men and in women) [1].
    Patrizia Ferroni1*, Mario Roselli2 and Fiorella Guadagni1
    Cancer patients are characterized by an acquired thrombophilic condition predisposing to increased risk of venous thromboembolism (VTE) [1]. Former studies have probably underestimated VTE incidence, since most of them were retrospectively conducted on patients cohorts recruited before the advent of targeted therapies, or have been focusing only on objectively confirmed symptomatic VTE.
    Yonggang Ma1* and Merry L. Lindsey1,2
    Following myocardial infarction (MI), cardiomyocytedeath in the area downstream of the arterial occlusion initiates an acute inflammatory response. Neutrophils are the first responder leukocytes recruited into the ischemic area [1]. In addition to directly regulating acute inflammation, neutrophils pave the signaling way for subsequent macrophage infiltration by releasing a wide range of cytokines, chemokines, and granule components [2,3].
    Oleksandr Kondrachuk*
    Vascular rings are a group of congenital aortic arch anomalies in which the trachea and esophagus are partially or completely surrounded by vascular structures. Patients with vascular rings may present with breathing or feeding difficulties.
    Panneerselvam Arunkumar*
    Atherosclerosis is a complex process with long natural history that culminates in obstructive coronary artery disease [1]. Percutaneous coronary intervention with drug eluting stent (DES) has revolutionized the management of varying forms of acute coronary syndrome and stable coronary artery disease (CAD) [2].
    Waqas Qureshi1* and Fatima Khalid2
    With aging population, cancer and cardiovascular disease are on the rise. Almost 1.6 million new cancer diagnoses and 0.6 million cancer deaths are projected to occur in United States in 2013 [1]. Almost a third (78 million) of US adults (≥20 years old) have one or more cardiovascular disease [2].
    Jin Kyung Kim*
    Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in developed nations [1,2]. Undoubtedly, the need for understanding pathophysiology of and advancing therapy for the myriad of disabling and/or fatal cardiovascular conditions is immense. This need is in part reflected by the sheer extent of ongoing basic science, translational and clinical research in the field, leading to the explosion of published discoveries that impact our knowledge and the way we care for patients with CVD. There is currently more than 270 scientific journals dedicated to topics of cardiology and cardiovascular medicine, and the number is increasing.
  • Current Issue Highlights
  • BRAVascular rings are a group of congenital aortic arch anomalies in which the trachea and esophagus are partially or completely surrounded by vascular structures.
    Readmore...

    Heart failure accounts for more than 34% of deaths in the US [1]. The pathogenesis of heart failure after myocardial infarction (MI) is served by changes in left ventricle size,
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