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  • ISSN: 2573-1297
    Volume 1, Issue 1
    Nandan Kumar Mondal*
    When scientists were sorting out the mysteries of cardiac and pulmonary cells, they may not have realized how their findings would apply to the use of surgical implants for coronary artery disease or to treatments for reducing high blood pressure or cardiac failure. Their primary target may focused to know how cells contract or how bio-molecules enter cells and change cellular activity.
    Thierry V. Scohy*, Stephan AV. Leutscher, Mohamed Bentala, and Bastiaan M. Gerritse
    A 43-year-old patient with the diagnosis of paravalvular leakage one year after mechanical mitral valve (MV) replacement was scheduled for minimal invasive mitral MV repair. Intra-operatively a standard three-dimensional transesophageal echocardiography (3D TEE) and 2D TEE examination were performed.
    Visual inspection and manipulation of the MV showed a good seal on the anterior side. The posterior side showed no bonding over an area of 1.5 cm located adjacent of the lateral commissure. But the 3D TEE color Doppler (CD) vena contracta (VC) image showed a much larger extent of leak than demonstrated in the surgical field. Based on the extent and location of the VC, the left atrial retractor was repositioned and re-inspection of the MV revealed an extra no bonding area of 1.5 cm on the anterior side of the lateral commissure.
    We conclude that 3D-TEE CD VC can alter surgical management and preserved our patient from an extra episode on extracorporeal circulation.
    Case Report
    Nicole Fink-Neuboeck*, Joerg Lindenmann, Elisabeth Smolle, Alfred Maier, and Freyia Maria Smolle-Juettner
    Non-small-cell lung cancer within congenital intralobar pulmonary sequestration represents a very rare coincidence. To our best knowledge, only twelve cases of pulmonary neoplasia associated with intralobar sequestration have been published.
    A 46 year old female patient, non-smoker, presented with recurrent episodes of fever and fatigue persisting over several months. Routine chest roentgenogram showed a high-density mass in the right lower lobe close to the diaphragmatic surface. CT-scan revealed a 4 x 3 x 8 cm mass in the posterobasal segment of the right lower lobe with systemic arterial supply from two large caliber vessels originating from the celiac artery and draining into the pulmonary vein.
    During segmental resection the sequester could not be separated from the diaphragm, a small part of which was also resected. Surprisingly, definitive histopathological examination revealed pulmonary adenocarcinoma pG3, pT3 within the intralobar sequestration. Our case and the review of the cases from the literature underline the suggestion, that pulmonary sequestration should be resected rather than undergoing treatment by embolization.
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