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  • ISSN: 2373-9487
    Volume 8, Issue 1
    Research Article
    Reed B Hogan II*, James A Underwood, Cynthia Wright, Lisa S Lestina, David G Mangels, and Terry O’Toole DO
    Background: Colonoscopy is the most common practice for the evaluation of the lower gastrointestinal tract. High-quality bowel preparation is imperative to ensure adequate visualization and surveillance of colon neoplasia. It has been reported that approximately 20% of outpatients have inadequate colon preparation, in part due to difficulties associated with the traditional purgative-based oral prep. An FDA-cleared, prescription-based, open system to purge the colon with water before colonoscopy is available and provides an alternative to oral prep.
    Aim: Evaluating the clinical outcomes, safety, adequacy, and patients’ satisfaction of the high-volume colon irrigation bowel prep for colonoscopy prescribed by physicians from two independent endoscopy centers.
    Methods: This retrospective study provides data analysis of 3,050 consecutive bowel prep procedures prescribed by 35 gastroenterologists. Patients’ demographics and safety data were recorded by the technical staff following stringent protocols. The examining physician provided bowel preparation adequacy, and patients’ satisfaction was recorded using post-procedure surveys.
    Results: The high-volume colon irrigation provided 97% adequacy with no serious adverse events, reflecting its efficacy and safety. The study presented excellent patients’ satisfaction and willingness to repeat. The outcomes were maintained regardless of the patients’ age, gender, pre-prep regime, and underlying diseases.
    Conclusion: Open system high-volume colon irrigation used under stringent standardized protocols is a favorable strategy for colonoscopy prep. Adopting this technology can lead to increased effectiveness and improved patients’ procedural experience, thus reducing the healthcare system’s costs associated with canceled, failed, and inadequate colonoscopies.
    Short Communication
    Patrick Viet-Quoc Nguyen*
    Background: Proton pump inhibitors (PPI) are widely used for the treatment gastrointestinal diseases. The use of PPI is not without risk as it is associated with many conditions such as osteoporosis or hypomagnesemia. The objective of this study was to assess PPI prescriptions in an ambulatory setting.
    Methods: Older adults presenting at the emergency department of a teaching hospital were prospectively assessed for use of a PPI at home. On the basis of a patient interview and a review of their medical record, the appropriateness of PPI prescription was evaluated according to the current guidelines in the province of Quebec.
    Results: During the study period, 2417 patients were screened and 536 older adults were included in the study. Using the PPI practice guideline, 184 patients (34.3%) were prescribed a PPI for an inappropriate indication.
    Conclusion: In conclusion, inappropriate PPI prescription remains an important issue in the older population since it exposes may older adults to a risk of adverse reaction without a proper indication. It is therefore of the utmost importance to reassess the indication of PPI every time it is prescribed.
    Clinical Image
    Xochiquetzal Sanchez* and Jose Ernesto Santiago
    A 71-year-old woman, with history of chronic ingestion of non-steroidal anti-inflammatory drugs previously diagnosed with osteoporosis, currently under treatment with calcium and vitamin D.
    Case Series
    Osnaya-Romero N, Conrrado S and Dautt P
    Polycystic kidney disease is an inherited disease that can lead to high blood pressure and kidney failure. In Mexico, 4.5% of patients with kidney failure are carriers of this disease; the liver is another of the organs affected by this disease that can manifest as abdominal pain and a mass effect in the abdominal cavity; we present 2 cases of polycystic kidney and liver disease (mother and child), in addition to describing the clinical manifestations, two different stages of the disease are shown, being a hereditary disease it is suggested that once a case is identified, an abdominal ultrasound is performed to first-degree relatives in search of cystic lesions to indicate preventive measures that help us preserve the overall well-being of the patient.
    Letter to the Editor
    Negar Shaterian and Negin Shaterian*
    Gastrointestinal problems are very common during pregnancy, that one of these problems is diarrhea and others are pica, gastroesophageal reflux disease, constipation, and hemorrhoids. However, the question is why these discomforts are very common in pregnant women? Because pregnancy causes physiologic and dramatic anatomic changes in women. These conditions have enough potential that leads to gastrointestinal discomforts such as diarrhea in pregnant women [1].
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