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  • ISSN: 2334-1815
    Current Issue
    Volume 6, Issue 3
    Research Article
    Gokulalakshmi Elayaperumal, Bhaskaran Sathyapriya, and Vanitha Chinnathambi M*
    Fish scale wastes are generally discarded in the environment through fish processing industries and local market vendors. It is one of the excellent and efficient renewable bioproduct. Consequently, a number of bioactive compounds have been identified including bioactive peptides, collagen, chitosan, and gelatin which are commercially marketed. In this present study, we used fish scale waste to extract chitosan polysaccharide and generated chitosan nanoparticles in order to use it for the application purposes. The synthesized chitosan nanosubstances were categorized by Field Emission Scanning Electron Microscopy (FESEM). In application, the potential use of fish scale nanoparticles as adsorbent for textile dye effluent was investigated under optimized conditions. Antimicrobial activity of synthesized chitosan nanoparticles was performed on various pathogens.
    The viability of utilizing fish scales as an economical bio- adsorbent for elimination of textile dye was studied on industrial effluent. Dye adsorption was studied by means of Fourier transform infrared spectroscopy (FTIR) before and after the dye treatment. The effluent was treated with chitosan nanoparticles and the pH and turbidity of the effluent was measured by Biochemical Oxygen Demand (BOD) and Chemical Oxygen Demand (COD) assay. The highest flocculation efficiency of chitosan was observed under these conditions. With chitosan nanoparticle treatment, removal of COD was improved to 80% and the turbidity removal efficiency was improved up to 90%.
    These results show inexpensively feasible slant for making of polysaccharide- chitosan from fish waste extract. Thus, the present study provides an excellent bio-adsorbent chitosan nanoparticle generated from fish scales, which have potential application as an adsorbent in bioremediation like wastewater treatment.
    Review Article
    Fatma Sami El-banna, Magdy Mafouz, Maged Elkemary and Nemany AN Hanafy*
    Gold nanoparticles (AuNPs) have obtained interest of scientists for many years. Their features exhibit enhanced optical and electromagnetic properties. For this reason, they are mostly applied for biomedical diagnosis and imaging. Besides that, they are being functionalized as a drug delivery system due to their small size. Since, this size gives them possible penetration into hard tissues. Furthermore, they are more suitable for specific targeting to mitochondria and nucleus. Recently, AuNPs can be modified by surface coating or by being doped with different metals. The results enhanced their potential use in many fields especially for plasmon resonance and bio-imaging. In our review, modification of AuNPs was overviewed.
    Ahmed Magdy, Emad Sadaka, Maged Elkemary and Nemany AN Hanafy*
    Silver nanoparticles exhibit great potential applications as anti microbial agents due to their strong inhibition for microbial growth. However, they can be used with drug delivery system in limitation. Nicked silver nanoparticles can produce free radical causing later mitochondrial dysfunction allowing initialing apoptotic process. In this review, liver as the main target for silver nanoparticles accumulation was overviewed. The mechanism by which silver nanoparticles can produce free radical was highlighted. Finally, it is recommended to functionalize silver nanoparticles with biodegradable polymers conjugated with ligand for certain and specific biomedical purposes.
    Joshy KS, Snigdha S, Anne George, Nandakumar Kalarikkal, Laly A. Pothen, and Sabu Thomas*
    HIV/AIDS has been major source of concern all over the world for past few decades. The current treatment regimes include the use of antiviral drugs belonging to the classes of nucleoside-analog reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). The use of highly active antiretroviral therapy (HAART) using multiple drugs, has raised the life expectancy of HIV-infected patients. However, the HIV infections, is yet to be targeted in anatomical reservoirs, such as the brain, testes, gut, liver, kidney, and secondary lymphoid tissue. Potential nanocarriers have been studied and analysed thoroughly to overcome the hurdles in the delivery of antiretroviral drugs for HIV prevention and therapy. This review provides an insight into the life cycle and infection of HIV and various nanoparticulate delivery vehicles used for anti-retroviral drugs. Biocompatible polymeric nanoparticles, liposomes and hybrid nanosystems have been thoroughly discussed. Such nanostructured materials hold great promise for the future of HIV treatment and can be expected to improve the quality of life of HIV victims.
  • Current Issue Highlights
  • Principles and applications of dielectrophoresis (DEP) of biomolecules, suspended in aqueous medium, are reviewed.
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    In this work, microporous TiO2 photocatalyst (IL-TiO2) with high photocatalytic performance was prepared via a sol-gel method using the ionic solvent
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