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  • ISSN: 2373-9479
    Early Online
    Volume 6, Issue 1
    Research Article
    Charles H. Crawford, Jeffrey L. Gum, Lawrence G. Lenke, Jacob M Buchowski, Charles C. Edwards, Steven D. Glassman, and Leah Y. Carreon*
    In an effort to reduce the rate of Surgical Site Infections (SSIs), recent studies have reported using intrawound, topical vancomycin powder. Although cost-effective and promising results have been published, there is concern for development of antibiotic resistance and catastrophic superbug infections. The purpose of this study was to evaluate and compare the culture profile of Surgical Site Infection (SSI) in patients undergoing posterior lumbar instrumented fusions with topical vancomycin powder utilized versus controls prior to the use of topical vancomycin powder. Patients who had a posterior lumbar instrumented fusion and subsequently developed SSI requiring operative treatment from June 2007 to June 2008 and from June 2011 to June 2012 were identified. Standard demographic and surgical data were collected. Culture results and timing of the SSI relative to index surgery were also collected. Comparison of SSIs pre-vancomycin (2007-2008) and post-vancomycin (2011-2012) identified 31 versus 26 patients, respectively; no difference in demographic or surgical characteristics between time-dependent cohorts. There was no difference in the culture profile between groups (p=0.667). When comparing the culture profile of surgical site infections after posterior lumbar instrumented fusions, there appears to be no difference comparing a pre-Vancomycin interval versus a post-vancomycin interval. Additionally, comparing SSIs with or without topical vancomycin, regardless of time interval, showed no difference in culture profile. The results of this study suggest that topical vancomycin powder did not increase the incidence of vancomycin-resistant, super bug infections in the time period studied. Continued surveillance of this increasingly common practice is warranted.
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