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  • ISSN: 2379-948X
    Volume 4, Issue 1
    Case Report
    Ricardo Caiado*, Ana Melo, Joao Eloi, Jose Bastos, and Pedro Tome
    Introduction: In several hematological pathologies (eg myelofibrosis, chronic hemolytic anemia, etc.), when hematopoiesis function of the bone marrow is insufficient, the phenomenon of extramedullary hematopoiesis may occur. Although hematopoietic tissue has a tendency to form masses that can be found in almost any part of the body, it rarely appears in nose and paranasal sinuses.
    Case presentation: The authors present a male patient, 75 years old, observed in Otorhinolaryngology consultation with epistaxis of the right nasal fossa and progressive nasal obstruction with a 6 months evolution. Besides intermittent cacosmiano other complaints were related by the patient.
    Relevant previous medical history: myelofibrosis JAK 2 positive and chronic autoimmune hemolytic anemia.
    The patient examination presented a friable injury in the right nasal cavity. A paranasal sinuses CT scan was requested to characterize the injury and a biopsy was scheduled. CT scan revealed an expansive lesion fully filling the right maxillary sinus with extension to the right nasal fossa. Two biopsies were performed but their results were inconclusive. A biopsy/excision of the lesion in the operating room lead to a extramedullary nasal hematopoiesis diagnostic.
    Conclusion: Hematological diseases often have a clinical presentation with signs and symptoms of the otorhinolaryngological area. Whenever pathology with atypical evolution arises these should be considered as a possible diagnostic. Since extramedullary nasal and paranasal sinus hematopoiesis is a rare entity, each case should be individually addressed, according to the signs and symptoms, and the patient's comorbidities.
    Miranda Morrison, Nils Guinand, Angeliki Alianou, Minerva Becker and Pascal Senn*
    We hereby present the case of a 32 year old patient with sudden sensorineural hearing loss (SNHL) and an MRI compatible with acute intra-cochlear hemorrhage.
    Spontaneous intra-labyrinthine bleeding is a rare cause of SNHL. Bleeding into the membranous labyrinth may lead to high concentrations of blood byproducts. Commonly affected subsites are the basal turn of the cochlea and the vestibule. Depending on the time lapse between the acute event and imaging, as well as on the concentration of the different blood products (methemoglobin), the signal intensity on T1/T2 weighted sequences may vary. Recent articles show that 3D FLAIR imaging is more sensitive than other MRI sequences for the detection of intra-labyrinthine hemorrhage.
    Conclusion: Although rare, SNHL may be caused by pathologies that are visible on MRI imaging. MRI FLAIR Imaging allows not only for the detection of the hemorrhage itself but also permits a differentiation from other causes of hypersignal in MRI such as lipomas, which can also cause SSNHL.
    David Oddo*, Gonzalo P. Méndez, Pablo Villanueva, Isidro Huete, Claudio Callejas, and José Lorenzoni
    Foreign vegetable material is an extremely rare finding in biopsies, especially from the upper respiratory tract. The frequency of paranasal fungal balls has shown an increase during last years, with the consequent higher number of biopsies performed and available for analysis. We present the case of a 50 year-old patient with an aspergilloma of the sphenoidal sinus that also revealed foreign material consistent with vegetable hairs. Their particular structure observed by histological analysis allowed the correct recognition of this very unusual foreign body of the upper respiratory tract.
    S.M. Abul Hasan, S.M. Mahmudul Hasan*, Muhammad Giashuddin, and Sumia Afrin
    Purpose: To report the case for guideline for proper diagnosis & management of such a case. A 40 years woman, non-diabetic, non-hypertensive, presented with swelling over the left lacrimal sac region, swelling on the upper left buccal area & watering from the left eye with giving the history of operation (DCR) in the left sac region. Based on the clinical findings, documentation & sac sac patency test, the patient was diagnosed as a case of failed DCR with periorbital abscess & periapical abscess of upper left canine tooth.
    Review Article
    Mette Pedersen*, Sanila Mahmood, and Bilal H. Akram
    This study examines how voice, respiration and brain regulation are connected. It observes how the anatomical mechanisms of respiration are connected to the physiological mechanisms. In this study, a British Library London search was made. For the latest 5 years 32 references were found, but no articles were found that covered the subject. Further research, restricted to respiration, was made through the database PubMed. Few relevant articles were found. This search shows that the area has not been a major subject and further research is necessary.
    Especially the pre-Bötzinger complex's influence on the rhythmogenesis of respiration is of interest. The pre-Bötzinger complex is situated in the brain stem, where the whole respiratory center is located. Respiration and voicing is connected to each other, as breathing control is very important to carry out precise control of vocal fold movement. Furthermore, certain parts of the brain show functional connections both when carrying out controlled breathing and pronouncing syllables. The aspects thereof are discussed, related also to voice therapy.
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