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  • ISSN: 2379-948X
    Volume 4, Issue 4
    Short Communication
    Jessica Sofranko Kisenwether* and Robert A. Prosek
    The purpose of this study was to examine the relationship among the various forms of amplitude and period perturbation. Long-term and short-term period and amplitude perturbation measures were obtained using a sustained vowel produced by normal speakers. Short-term measures of period and amplitude perturbation were highly correlated with one another in both men and women. Long-term measures of period perturbation were highly correlated among men, but moderately correlated for smooth pitch period perturbation quotient, and not correlated for fundamental frequency variation, among women. In both males and females, long-term amplitude perturbation measures were moderately correlated. As a result, only one short-term and one long-term measure of period and amplitude perturbation may be necessary for clinical judgments.
    Review Article
    Galdino Eliasib Hernandez-Vaquero, German A. Soto-Galindo, and Jose Luis Trevino Gonzalez*
    Otitis media is a disease characterized by the presence of inflammation of infectious or non-infectious origin facilitated by dysfunction of the Eustachian tube, it occurs mostly in children due to their anatomical characteristics. The most frequent isolated agent is Streptococcus pneumoniae being the most common chief complaint in children. The main important risk factors are: absence of breastfeeding, use of the pacifier, assistance to daycare among others. Four clinical stages of the disease can be differentiated, tubotympanitis, hyperemia, exudative stage and suppurative stage. The diagnosis of certainty is based on the presence of acute symptoms of infection, evidence of inflammation and effusion in the middle ear. However, the diagnosis can be suspected with a high degree of certainty in patients with otalgia without an appropriate otoscopy, or with the presence of exudate in the otoscopy without otalgia or otorrhea.
    Acute otitis media poorly treated can have serious complications such as facial nerve palsy, acute mastoiditis and acute bacterial meningitis. However, they are currently uncommon due to improvements in treatment regimens. The basis of the initial treatment in acute otitis media is observation during the first 48-72h and in case of therapeutic failure, the administration of high doses of amoxicillin for 5 to 10 days is recommended. In case of previous use of antibiotics or failure in the initial antibiotic therapy scheme a change of antibiotic should be considered, individualizing the condition of the patient based on the therapeutic guidelines.
    German A. Soto-Galindo and José Luis Trevino Gonzalez*
    Epistaxis is a nose hemorrhage of a very variable severity. This entity is the most frequent chief complaint in the emergency room involving the Otolaryngology Department. It is categorized into anterior and posterior epistaxis depending on the affected area. Anterior bleedings are easier to treat and luckily they account to the 80% of cases. The correct identification of the bleeding site and its etiology is vitally important for a successful treatment. Visualization of the bleeding site is usually achieved by rhinoscopy, but in some cases nasal endoscopy is needed. The first measure that needs to be taken is local pressure. If the bleeding persists, the correct identification of the site and chemical cauterization with silver nitrate should be performed. Electrical cauterization is indicated if the previous treatment fails. Surgical intervention is recommended if bleedings are refractory to conservative treatment. There is a variety of surgical approaches with specific indications and different success rates described in the manuscript.
    Case Report
    Sanjay Munjal*
    Alpha-thalassemia is a hereditary disorder which generally occurs due to one or more deletions of the alpha-globin chain loci. There is a wide spectrum of phenotypic presentations, from clinically asymptomatic to mild to severe anemia. Hearing loss is prevalent in major thalassemia but has not been reported in carrier alpha thalassemia. Here we present a case with alpha-thalassemia with deletion of homozygous traits that had bilateral sensorineural hearing loss which might have developed due to defect in the production of oxygen-carrying pigments. It is hypothesized that the poor oxygen carrying capacity of the blood supply in the cochlea may be possible cause of hearing loss. Here it can be emphasized that cases with thalassemia should be screened for hearing loss so that it can be identified and managed at early stage.
    Alice Prevost, Cristina Livideanu, Zoe Cavallier, Franck Boutault, Frederic Lauwers, and Raphael Lopez*
    The incidence of buccofacial manifestations of systemic sclerosis and their impact on patients' quality of life are often underestimated. We present the case of a 68-year-old female patient with significant microstomia that was impeding her oral hygiene care and feeding. Considering the absence of a generally agreed treatment and the wish of the patient to benefit from a quick safe and mini-invasive treatment we purpose perioral injections of PRP at the rate of one session per month. After one and a half years of treatment, we obtained an improvement in interlabial distance with improvement in the MHISS score (42 to 10), significant weight gain and an improved Rodnan score (3 to 1). Given these encouraging results, we decided to conduct a feasibility study, currently underway.
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