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  • ISSN: 2333-7079
    Volume 8, Issue 3
    Research Article
    Jokotade O. Adeleye, Aduragbenro DA Adedapo*, Jerry V. Amwe, Mabel A Charles-Davies, Taiwo R Kotila, Oluyemi Agbedana, Mathew Akin Ogunlakin, and Funmilola Aduke Mapayi
    Aim: To access drug utilization pattern of glucose lowering agents and relationship with glycemic control amongst patients with type 2 diabetes in an outpatient.
    Method: A cross-sectional study was conducted amongst patients with diabetes attending the Medical Outpatient clinic of the University College Hospital, Ibadan. Demographic data, drug utilization pattern, HbA1C test and side effects related glucose lowering agents were summarized using descriptive statistics. Glucose lowering agents were classified according to the Anatomical Therapeutic Chemical (ATC), classification system.
    Results: A total of 100 participants with type 2 diabetes took part in this study. 71% were females and 29% were males. The mean diabetes duration of the patients was 7.86±6.53 years. When stratified according to age groups, patients within the age group of 61-70 years were the highest proportion (56%). Metformin was the most commonly prescribed medication (21%). Majority of the patients (65%), were on combination therapy. 64% of patients had good glycemic control. The most common co-morbid condition was hypertension while hypoglycemia was the most common side effects reported by the patients.
    Conclusions: Metformin was the most commonly prescribed oral glucose lowering agent with most of the patients having good glycemic control.
    Abdourahamane DIARA*, Tidiane DIALLO, Souleymane Papa COULIBALY, Mariam FANE, Cheick Abou COULIBALY, Ousmane DEMBELE, Benoit Yaranga KOUMARE, and Ababacar MAIGA
    Context: In Mali, as in many countries, addictive substances constitute a growing public health problem given the multiplicity of substances used and the complexity of its socio-health consequences.
    Objective: Describe the profile of addictive substances in the psychiatry service of the Point G University Hospital Center.
    Method: This is a retrospective study (2015-2017), by including all the files whose diagnostic hypothesis was in favor of drug addiction recorded at the Psychiatry Service of the Point G University Hospital, Bamako, Mali.
    Results: Cannabis (30.8%), was the most consumed drug with a very significant p <0.01 binding compared to other products. It was followed by tobacco (25%), alcohol (17.4%), and tramadol hydrochloride (6.4%). Poly-drug addiction was confirmed by 80.7% of patients, with a minimum combination of two different addictive products (alcohol / promethazine / tobacco, tramadol hydrochloride / cannabis / clonazepam, etc.). Certain drugs in the class of analgesics, benzodiazepines, and neuroleptics were diverted from their therapeutic uses for addictive purposes. The most common disorders were those of the central nervous system.
    Conclusion: Addictive substances generate new drug addictions plus multiple and variable addictive behaviors which lead to many unknowns.
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