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  • ISSN: 2374-0124
    Volume 9, Issue 2
    Research Article
    Neaz Mujeri*
    The report examines the consequences of the sedentary behaviour of city dwellers since the nationwide lock-down that began following the novel coronavirus (COVIC 19), pandemic globally. To focus on specific group behaviour, the report takes on the EMBA students of IUB as the target population. Relevant data were primarily gathered from secondary sources. Two case studies were conducted involving purposively selected EMBA students from IUB to cover specific contexts behind the coronavirus outbreak and ensuing lock-down impacts. The study indicates that the city dwellers including IUB graduate students are experiencing an increased level fear and tension because of the lock-down. Changes in daily lives of city dwellers have occurred particularly for IUB students such as staying at home, changing work habits to work from home as much as practicable, spending more time with family members and keep their morale high, do more household chores, shopping for groceries and other necessities online. Furthermore, the city dwellers and students are coping and adjusting their life styles during the lock-down with increased use of social media and mobile phones to stay in touch with family members and friends and overcome social isolation. The study recommends several measures for ensuring healthy life, both physical and mental, for the city dwellers including: undertake regular physical exercise at home to relieve the stress and negative emotions to prevent sedentary behaviour, stroll at a neighbourhood park or rooftop/home garden to relax while maintaining a safe social distance with others, scan local and international media for updates on the latest corona virus situation, use more social media, and mobile phones to avoid the consequences of social isolation. Finally, a major response is to follow the instructions put forth by the WHO and the national authority to prevent further spread of coronavirus. The sooner the adjustments are made, the better will be the changed life style and the less the danger of COVID 19.
    Lucas de Alencar Viana Melo, Amanda Maria Costa Silva, Sarah Ellen Ribeiro Grangeiro, Wantuil Matias Neto, Luis Luciano Neto, André Alencar Moreira, Modesto Leite Rolim Neto*
    Introduction: Cerebrovascular Accident (CVA), is a neurological disorder whose pathophysiology of ischemic side occurs along with the development of a central inflammatory process. Omega-3 fatty acids appear as a potential agent in the prevention and treatment of the repercussions of this ischemic event, presenting the potential for neuroprotection in successive studies. 
    Objective: We aim to carry out a systematic review of the literature about the neuroprotective potential of omega-3 in terms of preventive and therapeutic aspects in ischemic CVA. 
    Method: From a search in the electronic databases PubMed and Scopus following the items of Guidelines for Systematic Reviews and Meta-analyzes (PRISMA), 12 published articles were included in the final sample and applied for discussion according to the literature. 
    Results: The studies pointed out the decrease in omega-3 as prejudicial to the regeneration of nervous tissues, as well as the neuroprotective role of omega-3 in cerebral ischemia after ischemia-reperfusion injury in animal models. 
    Conclusion: Reduction of cerebral edema, promotion of angiogenesis, preservation of the integrity of the blood-brain barrier and tissue protection were observed. Therefore, a greater understanding of the molecular role of omega-3 fatty acids and their consequences for supplementation in humans is needed.
    Sarah Ellen Ribeiro Grangeiro, Lucas de Alencar Viana Melo, Amanda Maria Costa Silva, Wantuil Matias Neto, Luis Luciano Neto, André Alencar Moreira, Modesto Leite Rolim Neto*
    Microcephaly is characterized by a complex etiology, in addition to being associated with congenital Zika virus infection, being caused by environmental, genetic factors, metabolism diseases, as well as by the use of drugs and maternal diseases during the gestational period. This study aimed to know the microcephaly in the maternal-child life cycle in the Cariri region and its repercussion on maternal mental health. This is a cross-sectional, descriptive research with a quantitative-qualitative approach, delineated through a descriptive study in the formal statistical analysis for quantitative results. Schutze’s narrative was used for qualitative analysis. The study was carried out in inland Ceará in a reference unit for children with microcephaly. Thirteen mothers were interviewed, who have children with microcephaly due to ZIKAV, who had contact with the virus during the fertile period during pregnancy. The profile of the study subject showed that maternal education corresponds to secondary education, 23.1%, with pardo self-reported color 92.3%, married marital status 61.5%, with 46.2% as housekeeper occupation, and the mean age of 29.38% (range: 15 to 41 years). The results showed that there is a difference between living conditions of families, knowledge about Zika virus and mothers’ feelings about this pathology. Therefore, public policies and health education should be implemented in relation to ZIKAV, in an attempt to reduce cases of microcephaly in the NE of Brazil.
    Mini Review
    Amanda Maria Costa Silva, Sarah Ellen Ribeiro Grangeiro, Lucas de Alencar Viana Melo, Wantuil Matias Neto, Luis Luciano Neto, André Alencar Moreira, and Modesto Leite Rolim Neto*
    Understanding the SARS-CoV-2 pathophysiology regarding neural system contamination and damage is necessary for clinical and therapeutic approaches, which may reduce the damage caused by the disease. In this regard, it is important to highlight that, besides the direct effect on neurons, the inflammatory state caused by a dysregulation of the immune system due to infection are both factors responsible for neurological phenomena of the disease. The presence of the virus in the bloodstream, its ability to directly penetrate the NS through peripheral nerves and the weakening of the blood-brain barrier are added to the tropism of SARS-CoV-2 by ACE-2 receptors, which favors the appearance of brain manifestations, associated with metabolic complications in the autoimmune processes induced by viral clinical condition. It is essential to remember that the cerebrovascular events have been increasingly reported in infected patients and are associated with the hypercoagulability caused by the disease. The activation of the coagulation cascade and deregulation of physiological anticoagulant mechanisms, such as protein C system and the disintegration of fibrin, are possible causes of this hypercoagulable state present in COVID-19. Even though it is still not evident whether the impairment of the nervous system is a result of direct infection by SARS-CoV-2 or of a diffuse inflammatory process affecting various organs and systems generating multiple manifestation, including those of the nervous system, we highlight that the quantity of drugs administered in intensive care units also can interfere with neurological conditions.
    Short Communication
    Dhana Ratna Shakya* and Naresh Man Bajracharya
    COVID-19 pandemic, soon after its appearance in China in November 2019, proved to be havoc and a great stressor in different forms and ways. Its effects and impacts depend on the multitude of the factors, including bio-psycho-social and circumstantial issues. One important aspect is the way we perceive, interpret and respond to the factors. Unhealthy strategy, to a great extent, results in complication and ill health while healthy way helps people to solve, cope and face the factor, problem, stressor or situation in future more efficiently. Religions have their different ways, angles, symbols, meaning, emphasis and medium of looking, perceiving, understanding, responding and facing with adverse situations, including pandemic. Here, an attempt will be made to briefly present the Buddhist way of looking into COVID-19 pandemic, with the hope that it will show path to go ahead in this new situation of dilemma and uncertainty.
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