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  • ISSN: 2378-9328
    Volume 2, Issue 3
    Research Article
    Fatemeh Setoodehzadeh, Zahra Kavosi, Ali Keshtkaran, Mohammad Khammarnia, Marzieh Eslahi and Maryam Kasraeian
    Abstract:
    Background: Type of delivery has impact on women postpartum quality of life) QL(. No study has investigated QL of after cesarean section (CS), natural vaginal delivery (NVD) and NVD with water birth as a novel method.
    Objectives: The aim of the study was to compare women postpartum QL after three delivery modes in Shiraz hospitals.
    Method: This cross-sectional study was conducted on the women after NVD, CS, and NVD with water birth at 2 months postpartum using a standard specific questionnaire of quality of life after child birth. Then, the data were analyzed using descriptive statistics and one-way analysis of variance (ANOVA) in SPSS, version 18.
    Results: NVD with water birth had highest mean score for mothers' feeling toward themselves, physical health, satisfaction with delivery, choice of the delivery method for future pregnancies and global health status compared to the CS and NVD group; however there was no significant association. There was significant association between NVD and CS with less economic burden (P<0.001) and feeling toward sexual intercourse (P=0.012), respectively.
    Conclusion: The type of delivery had association with women postpartum QL in two dimension of economic burden and sexual intercourse. It is suggested that pregnant women and obstetricians' knowledge toward NVD with water birth should be improved through appropriate education in delivery preparing courses.
    Ke-Sheng Wang*, Xuefeng Liu and Liang Wang
    Abstract:
    Background: Little is known about the associations of beliefs about cancer and knowledge of genetic testing with cancer information seeking behavior.
    Methods: We examined 401 cancer patients (321 cancer information seekers and 80 non-seekers) and 2,478 non-cancer individuals (1,142 cancer information seekers and 1,336 non-seekers) from the 2012 Health Information National Trends Survey (HINTS). Weighted univariate and multiple logistic regression analyses were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).
    Results: The overall prevalence of information seeker in cancer patients was 80.8% (83.5% for males and 78.3% for females); while the prevalence in past smoker (87.7%) was significantly higher (p=0.0476) than non-smoker (77.1%) and current smoker (72.8%). In non-cancer individuals, the overall prevalence of information seeker was 43.9% (38.9% for males and 48.9% for females, p=0016). Multiple logistic regression analyses showed that being female (OR=1.4, 95%CI=1.04-1.89, p=0.0278), higher education (OR=1.76, 95%CI=1.17-2.65, p=0.0072), strong belief in easily getting cancer (OR=2.83, 95%CI = 1.54-5.22, p=0.0008), and having knowledge of genetic testing (OR=1.58, 95%CI = 1.16-2.16, p=0.0042) were positively associated with cancer information seeking behavior, whereas weak belief in the effects of health behaviors on the development of cancer had negative association (OR=0.59, 95%CI = 0.41-0.86, p=0.0058).
    Conclusions: The overall prevalence of cancer information seeker was higher in cancer patients than in non-cancer individuals. In non-cancer adults, beliefs about cancer and knowledge of genetic testing were associated with cancer information seeking behavior. Increased knowledge of causes of cancer and genetic testing may increase the use of cancer information. Future studies with a larger sample are needed to confirm our current findings.
    Mini Review
    Stephen M Modell, Esha Mathew and Samantha E Greenberg
    Abstract:
    This review argues that though the Patient Protection and Affordable Care Act (ACA) and Medicaid Expansion have made headway into including genomic counseling and testing in the list of preventive services available to those at-risk for cancer, further steps may be taken. Cancer remains the second leading cause of death in the United States, with an aging population and an increasing proportion of racial-ethnic minorities. The ACA, and Medicaid and Medicare, have addressed hereditary breast and ovarian cancer in the general population and the underserved, following recommendations issued by the United States Preventive Services Task Force and interpretations by U.S. federal health agencies that allow for coverage of both counseling and testing. The loosening of gene patenting rules by the U.S. Supreme Court has also had a positive impact. Nevertheless, many low-income families remain ineligible for BRCA1/2 counseling and testing under Medicaid and Medicare, despite the recent expansions, and provision under the ACA depends on whether the individual meets qualifying criteria that are not monolithic. Coverage policy of another cancer condition of public health concern, Lynch syndrome, is still evolving. Our review outlines various gaps that remain in coverage policy, and identifies the roles that advocacy organizations and public health officials can play in fully realizing the availability of oncogenomic services to those in need.
    Short Communication
    Arvind Shukla, Nigamananda Dey, Prathanika Nandi, and Malika Ranjan
    Abstract:
    The current trend of burn wound care has shifted to a more holistic approach of improvement in the long-term form and function of the healed burn wounds and quality of life. This has demanded the emergence of various skin substitutes in the management of acute burn injury as well as post burn reconstructions. Skin substitutes have important roles in the treatment of deep dermal and full thickness wounds of various etiologies. At present, there is no ideal skin substitute in the market. Skin substitutes can be divided into two main classes, namely, biological and synthetic substitutes. The biological skin substitutes have a more intact extracellular matrix structure, while the synthetic skin substitutes can be synthesized on demand and can be modulated for specific purposes. Each class has its advantages and disadvantages. The biological skin substitutes may allow the construction of a more natural new dermis and allow excellent re-epithelialization characteristics due to the presence of a basement membrane. Acellular dermal scaffold are one of the types of biological skin substitutes which has the extracellular matrix (ECM) almost like the normal skin extracellular matrix. For regeneration and healing of deep burn wound, ECM plays a very important role in rapid healing with minimum scar. Although some acellular dermis based products are available in foreign market, their prohibitive high cost prevents the Indian patient population to use it. Hence, this Method was designed to prepare an acellular dermis, indigenously, suitable for clinical application. NaOH method was used to standardize the decellularization method. It was observed that 6 weeks of decellularization was sufficient to completely decellularize the skin. It was confirmed by H&E staining. The biocompatibility was confirmed by cell culture assay.
    Jose Navidad, David Bina, Manjeet Khubbar, Steve Gradus and Sanjib Bhattacharyya
    Abstract:
    The City of Milwaukee Health Department Laboratory (MHDL) collected a total of 320 viral gastroenteritis outbreak suspected specimens during the period of January 2006 – August 2013. Gastroenteritis infection (GI) suspected cases originated from long term care facilities, local hospitals, area restaurants, social events, and child care facilities. Nucleic acid from stool samples was tested for the presence of Norovirus (NoV) RNA using a real time RT-PCR assay targeting the highly conserved ORF1-ORF2 junction region of the Capsid gene. PCR analysis identified Norovirus as the GI causing agent in 141 (44% of specimens) of these cases. The majority of identified specimens were associated with global pandemic GII.4 genotypes (88.7%), with additional outbreaks closely related to more diverse NoV groups that co-circulated with the pandemic strains (11.3%). Our findings highlight the role of local health department laboratories in monitoring the genetic diversity of the currently circulating NoV strains, emergence of novel variants, and determining their potential implications in gastrointestinal outbreak management.
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