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  • ISSN: 2378-9344
    Current Issue
    Volume 7, Issue 3
    Review Article
    Nalaka Gunawansa* and Thilina Gunawardena
    Isolated distal deep vein thrombosis (IDDVT) accounts for approximately 50% of all patients diagnosed with DVT. While the definitive management of patients with proximal deep vein thrombosis is fairly well defined, IDDVT remains shrouded uncertainty. The great majority of patients with IDDVT may remain with little or no symptoms and have spontaneous resolution of the thrombi. However, a small but significant fraction may show proximal thrombus extension and may proceed to cause pulmonary embolism or late deep venous reflux. Identification of this subgroup of patients with IDDVT who have a greater propensity for thrombus extension or further sequalae remains the cornerstone of individualized management for optimal results.
    Case Report
    Kalman Polner, Gergely Gosi*, Istvan Vas, Gyorgy Acsady, Katalin Albert
    We present the clinical history of a peritoneal dialysis male patient who was diagnosed with rapidly progressing abdominal aortic and bilateral common iliac artery aneurysms after more than two years on CAPD treatment. The patient refused open repair of the aneurysms because he adhered to the convenient dialysis modality, so he underwent endovascular reconstruction. The next day after surgery he carried out CAPD treatment himself. We analyze the consequences of the complications and co-morbidities that 6 years after the procedure led to conversion to haemodialysis and 2 more years later the patient's death. We found the outcome of our patient outstanding compared to literature data of the clinical course and perioperative or late mortality of similar patients. High early mortality of end stage kidney disease patients after aneurysm surgery needs to be emphasized. To reduce this procedure is recommended as early as possible, ideally before starting dialysis. Open aneurysm repair is a lengthy, highly invasive procedure with the risk of significant blood loss that all contribute to higher morbidity and mortality. EVAR is recommended in this patient group in case of anatomical suitability. Postoperative complications of endovascular repair can remarkably be reduced by proper hydration and usage of as small amount of proper quality contrast material as possible. Regular follow-up is paramount to early reveal and treat complications that we deem substantial in our case.
    Research Article
    Kimberly M. Cheng*, Frederick G. Silversides, Shasha Liu, Ji Eun Kim, and Frederick C. Leung
    Objectives: (1) To use NGS to examine the differential liver gene expression in Japanese quail fed a cholesterol-enriched diet and to identify the gene systems that may be associated with the development of atherosclerosis, and
    (2) To see how divergent genetic selection and diet has modified the expression of these gene systems.
    Mini Review
    Simon Halevy*, Asefa Gebrewold, Anthony Carella, and Burton M. Altura*
    Deep vein thrombosis (DVT) is a prevalent syndrome, particularly in the aged, which often leads to significant morbidity and mortality. It also leads to costly, extended hospitalization. Pharmacologic manipulation and anti-coagulant drugs are the standard approaches to treatment of DVT patients. There are more than one million cases of DVT each year in the USA. Despite many decades of research, the precise vascular mechanisms still remain to be revealed [1].
    Short Note
    Kerzmann Arnaud*, Krzesinski Jean-Marie, Sakalihasan Natzi, and Defraigne Jean-Olivier
    Endovascular aneurysm repair (EVAR) is the preferred approach for treatment of abdominal aortic aneurysm (AAA) when anatomy is compatible. Early and medium term morbidity and mortality rates are lower with EVAR than open aortic repair (OAR). In the long term EVAR is however associated with higher reinterventions rate and lower survival [1].
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