2017 Volume 4 - Issue 1
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June 01, 2017 Mini ReviewAbstract Cumulative evidence shows that innate immunity participates in the pathogenesis of Alzheimer´s disease. This implies that activation of microglia by the so called “damaged signals” triggers a cascade of pathological molecular events thus leading.....
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July 07, 2017 Research ArticleAbstract Objective: Traditional Cognitive Training with paper-pencil tasks (PPCT) and Computer-Based Cognitive Training (C-BCT) both are effective for people with Mild Cognitive Impairment (MCI). The aim of this study is to evaluate the efficacy of a C-BCT pr.....
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December 10, 2016 Short CommunicationAbstract Endoplasmic reticulum (ER), a multifunctional organelle, plays an important role in the maintenance of intracellular calcium homeostasis and regulation of cell death. Cellular stress conditions such as glucose deprivation, depletion of ER calcium sto.....
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December 10, 2016 Research ArticleAbstract Objectives: This study aims to demonstrate the effectiveness of progressive music activation to improve selective attention in patients diagnosed with Alzheimer’s disease (AD) and healthy older adults. Methods: 58 residents of senior centers or .....
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December 28, 2016 Review ArticleAbstract It is well recognized that an imbalance of intracellular Ca2+ homeostasis contributes to the pathogenesis of neurodegenerative diseases, such as Alzheimer’s (AD). Therefore, regulation of intracellular Ca2+ homeostasis may represent a new target fo.....