2016 - Volume 1 - Issue 1 Articles
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Research Article | ArticleMay 23, 2016 | Pages : 205 - 450Abstract The biguanide metformin belongs to the cornerstone therapeutics in treating type II diabetes mellitus. Chronic treatment of diabetic patients with metformin also reduces the development of micro- and macrovascular complications including atherosclero.....
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Review Article | ArticleMay 13, 2016 | Pages : 205 - 450Abstract Ever since the results of the UKPDS 34 study were published in 1998, metformin has been considered as the first-line pharmacological treatment for type 2 diabetes. However, from several standpoints the UKPDS study was methodologically questionable. T.....
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Review Article | ArticleJune 04, 2016 | Pages : 205 - 450Abstract Metformin, being one of the oldest drugs, is the only biguanide agent currently available for treatment of diabetes mellitus. With data for its central role in treatment of glycemic and metabolic abnormalities as well as established safety profile an.....
