Peripheral Neural Regulation of Pregnancy Corpus Luteum - Abstract
The corpus luteum (CL) is an ovarian endocrine gland with limited functional life. The importance of this structure lies in the fact that its main product, progesterone, is essential for the maintenance of pregnancy. As result, mammals have developed a complex series of regulatory mechanisms to support its synthesis and secretion at appropriate levels through gestation. Peripheral innervation represents an additional regulatory mechanism to the classical endocrine. This has been studied through the use of ex vivo coeliac ganglion-superior ovarian nerve-ovary integrated system (CG-SON-O), which was incubated in buffer solution until 240 min, with the CG and the ovary located in different compartments and linked by the SON. This review focuses on the stimulus of different neural and hormonal agents on the CL of pregnancy through the CGSON-O system in the rat.