Peptides: A Novel Approach to Enhance Eyelash and Eyebrow Growth - Abstract
Purpose: Evaluate the safety and efficacy of topical peptides as a treatment to enhance eyelash and eyebrow appearance.
Subjects and methods: An open label cohort study over a period of 12 weeks was performed on healthy adult female subjects. All subjects daily applied a peptide extract
solution on their eyelids and eyebrow. They also attended a fortnightly microneedle session to apply the peptide extract solution on the eyelash and eyebrow. The length of the
eyelash was determined using an eyelash ruler while the overall eyelash appearance was assessed using the GEA scale. The eyebrows appearance was evaluated using digital
photography and assessed by two independent dermatologist while individual eyebrow follicle thickness and the presence of new eyebrow hair follicles were evaluated using the
Micro skin and hair diagnostic device (EW-EWB-1007-307, Germany).
Results: The peptide extract solution significantly increased the length of the eyelash by 3.7± 1.4mm (p = 0.014). There was a 100% improvement in the GEA scale evaluation,
where 83% showed a one-grade improvement while the remaining 17% demonstrated a 17% improvement. Eyebrow analyser scans showed an increased thickness in individual
eyebrow thickness and there were the presence of many new eyebrow hair follicles at the end of the 12 weeks.
Conclusion: Peptide extract solution is a safe and efficient treatment to enhance eyelash and eyebrow appearance without causing any major adverse reactions.