Clinicopathological Profile of Colorectal Cancer Patients in Suez Canal University Hospitals-Egypt - Abstract
Introduction: Colorectal cancer (CRC) is the third most common malignancy and the fourth leading cause of cancer death worldwide. In Egypt, it is the six cancers in both males and females. This study was performed to define the epidemiological and clinicopathological characteristics of CRC in Egypt. Material and Methods: Retrospective study included all patients diagnosed with colorectal carcinoma at Suez Canal University Hospitals, Egypt from January 2006 to December 2016.
Results: A total of 193 patients were included in this study, 57% were females and 43% were males. Colon cancer were more common than those located in the rectum, (58.6% vs. 25.4%), the ascending colon was the commonest location (56.2%). Descending colon and rectum were equally the commonest in females (29.1%) while the ascending colon was the commonest in males (28.9%). Most tumors were adenocarcinoma (76.2%). In terms of tumor markers, CEA was elevated in 45.6% and CA19.9 was elevated in 40.9% in preoperative evaluation. Most patients presented with stage II (30.6%). Liver was the most
common metastatic site (67.6%). The overall survival was 18.8 month.
Conclusion: Colon cancer is more frequent than rectum cancer where ascending colon is the most affected sub site. The mean age at diagnosis was 52.6 years with female predominance. Most patients had tumors that were adenocarcinoma, low grade and most presented in stage II. Liver is the commonest metastatic site. The overall survival was 18.8 month. Three-year and 5-years survival rate were 16.1% and 3.6%