Rotashock Therapy: An Observational Study - Abstract
Introduction: Thrombocytopenia in patients undergoing major heart surgery, is a common event. Various events such as cardiopulmonary bypass induced platelet damage and
hypothermia are known as contributing factors but, exact role of CBP application has not been studied . The aim of this study is a comparison of acute change of platelet count and
functioning after coronary artery bypass surgery with or without cardiopulmonary pump.
Methods and Materials: Present study is a descriptive cross- sectional study, and performed on 200 patients’ candidate elective bypass coronary artery surgery. The patients
were allocated into two groups: on – pump as study group(N--100) and off- pump as control group (N=100). No intervention except bleeding time measurement was performed.
Demographic variables, bleeding time and platelet count were recorded before and after surgery.
Results: Results of this study showed that using of cardiopulmonary bypass in elective coronary artery bypass grafting significantly increased the operation time, need to
exploration, increased consumptiction of corticosteroid, noradrenalin and adrenalin. Also, Thrombocytopenia frequency (45% vs 20% Pvalue<0.001), platelet dysfunction and
subsequent increasing of BT (77.02 vs. 33.1% p=0.013), in comparison with off- pump surgery had statistically significant difference. Although, first day of bleeding rate was similar
in both groups but need to reoperation was higher in on- pump group.
Conclusion: Results showed that in comparison with off- pump CABG, using extracorporeal circulation can lead to further platelet count reduction and its function. Although; CBP
had no effect on amount of bleeding b at first day of postoperative period