Embolic Stroke of Undetermined Source in Iranian Population: A Subgroup Analysis from TOSSI Study - Abstract
Reported frequency of embolic stroke of undetermined source (ESUS) ranged from 7-33%. An estimated annual stroke recurrence risk in these patients is 2.3–6.8 % and, mortality rate is 5.2%. There is no documented data about ESUS frequency and the recurrence rate in Asia. Present study aimed to demonstrate, the incidence and recurrence rate of ESUS. We analyzed the ESUS subgroup data form TOSSI study and fallow them after 1 year by telephone call. All thromboembolic event including ischemic stroke, transient ischemic attack, myocardial infarction, pulmonary thromboemboli and deep vein thrombosis and all deaths was recorded. The rate of ESUS was 42.77%, higher than even reported data. ESUS recurred in 12.12% of patients during 1 year follow up. The annual mortality rate was 8.45%. In Conclusion, incidence, recurrence and mortality rate of ESUS in Iran is higher than international reported rates.