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  • ISSN: 2573-1173
    Early Online
    Volume 4, Issue 4
    Review Article
    Esen Kasapoglu Gunal*
    Sjogren's syndrome [SS] is an autoimmune disease of mainly exocrine glands. Sicca symptoms are the most common cause of admission to the outpatient clinics. However systemic involvement like lungs, peripheral nervous system, joints, liver, kidney can also be seen. SS is called primary SS [pSS] when SS is not accompanied by another autoimmune disease like rheumatoid arthritis, systemic lupus eritematozus [SLE] [1].
    Case Report
    Manoela Crisostomo*, Marilia Crisostomo, Marcio Crisostomo, and Raissa Oliveira
    Alopecia Areata (AA) is an autoimmune disease that can affects 1-2% of the population. Management of AA depends on the type of AA. Treatment include topical irritant, topical and intralesional steroids and, for severe cases, systemic corticosteroids, immunosuppressive drugs and immunomodulatory treatments. An uncommon and severe form of AA is Alopecia Areata Universalis (AAU) that involve hair loss over the entire scalp and body.
    We report a case of a 35 years old man, with AAU for 16 months developed after hypothyroidism. The suggested treatment was: a monthly Ablative Fractioned CO2 Laser in low fluence followed by steroid topical lotion at scalp. Laser power output was set at 6-7w, with a density of 300-500µm and a dwell time of 300ms (Mode Stack 1).
    The Fractioned Laser Therapy (FLT) is a second-line therapy in AA. It makes microscopic thermal columns in the dermis, minor trauma and wound healing itself can drive hair growth and can also be used as a Drug Delivery System with low side effects. Randomized controlled trials in a larger number of patients are required to confirm the efficacy of this treatment and optimal therapeutic parameters.
    Case Series
    Catherine Chapelon-Abric*, Anne-Claire Desbois, Caroline Dehais, Sophie Barthier, Christian de Gennes, David Saadoun, and Patrice Cacoub
    Breast involvement in sarcoidosis is rare, reported in less than 1% of cases. We report 3 new cases of breast sarcoidosis and analyzed the 22 previously published cases. Breast involvement was the only manifestation of sarcoidosis in only three cases while breast sarcoidosis was the site of sarcoidosis at presentation in 12 cases. Sarcoidosis was multi-systemic in 45% of the 25 cases. Except in one case, physical examination revealed multiple breast masses without skin/nipple changes or lymphadenopathy. X-ray, ultrasound of the breasts showed multiple irregular and/or spiculated hypoechoic masses without micro calcifications. MRI showed mass with gadolinium enhancement. Treatments, rarely given for BS rather than sarcoidosis, included steroids and immunosuppressant therapy, usually showed a good efficacy in these series.
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