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  • ISSN: 2373-938X
    VorinostatSAHA Promotes Hyper-Radiosensitivity in Wild Type p53 Human Glioblastoma Cells
    Authors: Eric Diss, NarasimhaRao Nalabothula, Duc Nguyen, Elizabeth Chang, Young Kwok, and France Carrier*
    Glioblastoma multiforme (GBM) is a very aggressive and locally invasive tumor. The current standard of care is partial brain radiation therapy (60 Gy) concurrently with the alkylating agent temozolomide (TMZ).
    A Novel Bioabsorbable Sleeve for Staple Line Reinforcement in Laparoscopic Sleeve Gastrectomy (LSG) For Morbid Obesity: Possible Usefulness for the Future Application in Operations for Alimentary Tract Cancers
    Authors: Chouhei Sakakura1*, Yuhki Ozamoto2, Takeshi Togawa2, Akeo Hagiwara2, Eigo Otsuji1, Hitoshi Fujiwara1, Kazuma Okamoto1, Daisuke Ichikawa1, Masayoshi Nakanishi1, Ken Kubota1, Noriaki Kuriu1, Hisashi Ikoma1, Atsushi Shiozaki1, Shuhei Komatsu1, Yasutoshi Murayama1, Rei Morimura1 and Hiroki Konishi1
     
    Extracellular Functions of Galectin-3: An Update
    Authors: Josiah Ochieng*
    Galectin-3 is a multifunctional protein which plays pivotal roles in cell physiology, covering diverse mechanisms ranging from immune surveillance [1] to metastatic spread of cancer [2].
    Latest Articles
    Case Report
    Maryum Nouman*, Mehwish Shaikh, Ghulam Haider, and Khalil Meher
    Objective: Myeloid sarcoma comprising of immature granulocytic cells is a rare, extra medullary tumor. Spinal cord compression caused by a myeloid sarcoma is even more so. This study reports a case of spinal myeloid sarcoma presenting with paraplegia.
    Patient and method: 18-year-old male presented with progressively worsening back pain leading to paraplegia. Magnetic resonance imaging (MRI) dorsal spine revealed a soft tissue mass extending from D4 through D8 causing compression of cord in mid dorsal region. The patient underwent surgical decompression. Histology confirmed the diagnosis of myeloid sarcoma. Post operatively bone marrow biopsy showed no evidence of myeloproliferative neoplasm. The patient then received systemic chemotherapy in line of Acute Myeloid Leukemia (AML).
    Result: After 9 months patient reports complete relief of symptoms. Post treatment MRI shows no evidence of compressive or residual disease.
    Conclusion: Spinal myeloid sarcoma presenting as paraplegia is very rare. We suggest that clinical suspicion can lead to early diagnosis and appropriate management.
  • Recent Articles
  • Extracellular Functions of Galectin-3: An Update
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    Biomarkers of Esophageal Cancer Comes of Age?
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