Is Primary Prevention of Breast Cancer Possible? - Abstract
The epidemiology and knowledge on risk factors for breast cancer, both endogenous and exogenous, is reviewed. It is concluded that primary prevention of breast cancer is possible, but that due to the long natural history of breast cancer, avoidance of risk factors should start early in life. Among the most important risk factors to avoid are alcohol, nulliparity, obesity in post-menopausal women, physical inactivity, tobacco smoking, and an unhealthy diet. It is estimated that if all risk factors for breast cancer could be avoided, the incidence of breast cancer in the West would eventually fall by over 50%.