Granulomatous Mastitis with Erythema Nodosum and Polyarthritis: A Rare Case Report and Review of Literatures - Abstract
A 31-year-old woman was referred with a painful mass and erythema in the left breast that was initially treated with antibiotics. Three weeks later, the mass and erythema had increased and polyarthritis and erythema nodosum had developed in both legs. In our hospital,A core needle biopsy of breast and leg
nodule led to a diagnosis of granulomatous mastitis with polyarthritis and erythema nodosum. High-dose prednisolone (15 mg x 3 daily) with indomethacin (25 mg x3 daily) for three week, rapidly improved the polyarthritis and the erythema nodosum. Granulomatous mastitis is a very rare, chronic inflammatory disease and only nine cases with granulomatous mastitis with erythema nodosum and polyarthritis have been described. We reviewed the literature to determine the clinical presentations, diagnosis, pathological features and treatment of granulomatous mastitis with erythema nodosum and polyarthritis. Appropriate
diagnosis with steroid therapy should result in excellent outcomes.