Paget’s Disease of the Vulva and Penis: A Mini Review - Abstract
Paget’s disease of the vulva appears as a patchy, reddish and whitish, velvety, and eczematous skin lesion. Women with Paget’s disease of the vulva are usually white and postmenopausal and complain of localized itching and burning. It is confined to the epithelium in most cases, but invasive disease is present in 13% to 25% of cases. If the disease appears to be intraepithelial, then wide local excision is recommended with
a margin of 1 to 2 cm. beyond the clinically visible lesion. The use of intraoperative frozen sections has been reported to reduce the incidence of positive margins on permanent sections and lower the risk of recurrences.