Study of Goblet Cell Morphology by Impression Cytology in Various Types of Pterygium - Abstract
Purpose: To evaluate ocular surface damage caused by pterygium by studying goblet cell morphology with the help of impression cytology and also to observe correlation of various grades and types of pterygium to changes in goblet cell morphology.
Material: 50 eyes with pterygium were classified according to site (nasal, temporal and double), morphology (corneal involvement) and nature (fleshy and other minor groups which included atrophic, cystic and recurrent) of pterygium. These eyes were studied for changes in goblet cell morphology by impression cytology and its correlation with different types and grades of pterygium.
Result: Interpretation of impression cytology was done by Saine et al., criteria. Incidence of grade 2 nasal fleshy (68.2%) ptyergium was commonest which showed grade 2 and 3 changes in goblet cell morphology. In minor group, atrophic pterygium was 12% out of which 75% had grade 2 impression cytology changes and recurrent pterygium showed grade 2 impression cytology changes.
Conclusion: Corneal involvement and nature of pterygium was directly proportional to changes in goblet cell morphology by impression cytology.