The Role of Helicobacter Pylori on the Complications of Peptic Ulcer - Abstract
Background and objectives: Helicobacter pylori(HP) infection represents one of the most common and medically prominent infections worldwide. Helicobacter pylori are found in 80-90% patients with peptic ulcer. However, there is paucity of reports on prevalence of H. pylori infection in patients with peptic ulcer perforation, bleeding or pyloric stenosis. The aim of this study was to assess the prevalence of H. pylori infection in patients undergoing laparotomy for repair of complications of peptic ulcer.
Patients and methods: The study was conducted retrospectively at Van state hospital between 15.10.1999-25.12.2000, and Trakya University, Medical Faculty in the department of General Surgery in Turkey between 15.11.1997-14.10.1999. Data were collected on patient’s age, sex, and the prevalence of H. pylori infection in patients undergoing laparotomy for repair of complications of peptic ulcer.
Results: There were 2 women and 24 men in this review with a mean age of 26,54 (range 18 to 48) years. Statistically significant relationship was found between HP positivity and complications of peptic ulcer. HP positivity was found in 22(85%) of patients with complications of peptic ulcer in this series. Cigarette smoking was found in all patients in this study.
Conclusions: Based on our findings, significant evidence suggests the potential role of HP infection and cigarette smoking in patients with complications of peptic ulcer. Also, the current data provide sufficient evidence to define the relationship between patients with complications of peptic ulcer and HP infection.