Clinicopathological Findings of Hydatid Cyst Disease: A Retrospective Analysis - Abstract
Background: Hydatid disease is a major public health problem that is spreading all over the world. We aimed to this retrospective study was to investigate clinical and histopathological features of patients with hydatid disease (HD).
Methods: Archival records of the 113 patients who diagnosed as hydatid cysts between 1997 and 2015 were analyzed retrospectively. Clinical and histopathological parameters were evaluated in all patients.
Results: Of 113 cases, 55.8% were female and 44.2% were male. Mean age was 38.3 years. The average diameter of cysts was 9.50 cm. Cysts were localized in liver (77.0%), soft tissue (5.3%), lungs (3.5%), spleen (2.7%), kidney (1.8%), cerebellum (0.9%), gall bladder (0.9%) and paraspinal site (0.9%). 7.1% of cases had multiple organ involvement. 101 cases had only one cyst and 12 cases had 2 or more cysts in the same organ. The histopathologic findings consistent laminated cyst wall, scolex and pericystic inflammatory infiltrate. All patients were treated with antihelminthic drug and surgery. The overall mortality rate was 0%.
Conclusions: Although HD is seen most often in the liver, it can be found in any part of the body. HD appears to be more common in females and between 25-50 ages. The optimal treatment is a total cystectomy regardless of the location. HD with unusual localizations may cause serious problems of diagnostic confusion and must be considered in the differential diagnosis of cystic lesions.