Analysis of Factors Related to Extubation Failure in Patients Submitted to Invasive Mechanical Ventilation - Abstract
Objective: To define the profile of patients submitted to Invasive Mechanical Ventilation (IMV), admitted to a Neonatal Intensive Care Unit (NICU), to identify factors related to
failure or failure in the extubation process.
Methods: A retrospective and analytical study, carried out between January 2017 and December 2018, at Maternidade Instituto Cândida Vargas (ICV), Brazil. 448 medical
records of patients undergoing IMV were identified. The variables related to the ventilatory modality in question were used, grouped in a database and analyzed by the Chi-square
and Mann Whitney tests with a 99% significance level to identify the main factors related to the failure of extubation.
Results: In a total of 448 identified patients, 9.3% of extubation failure was found. Weight, oxygen use time and IMV time are strongly related to extubation failure. The use
of the weaning protocol has a negative correlation in removing mechanical ventilation. The use of SBT did not show any influence on the success or not of extubation. The average
length of hospital stay for patients with extubation failure was more than twice as high as those who had no failure.
Conclusion: The study concludes that weight, duration of oxygen therapy and exposure to IMV are related to extubation failure. It was found that neonatal care with
interventions to prevent extubation failure can reduce the damage caused by the use of prolonged IMV. The best strategy for harm reduction is related to less invasive care, with the
use of good practices in ventilatory support.