Comparison of Anthropometric, Inflammatory and Metabolic Markers in 8-Year-Old Children from the Brasil Sul Cohort Study - Abstract
Aim of study: Compare anthropometric, inflammatory and metabolic characteristics in eutrophic and obese 8-year-old schoolchildren attending at a cohort in Palhoça/SC,
Brazil.
Methods: Cross-sectional analytical study involving 34 8-year-old students selected for convenience using the anthropometric measurements from obese or eutrophic individuals
according to their BMI. Anthropometric measurements were repeated at the clinic (weight, height, waist circumference and tricipital fold), and a clinical examination was also
performed. Biochemical measurements were performed for glucose, insulin, total cholesterol and HDL-cholesterol, triglycerides, ultra-sensitive C reactive protein (us-CRP), interleukin
(IL)-6, IL-1?, IL-10, tumor necrosis factor (TNF) and adiponectin. For the comparison of independent samples, Student’s t-test was used for parametric data or the Mann-Whitney test
for non-parametric data, after normality analysis by Shapiro-Wilk.
Results: Waist circumference (p= 0.002), the tricipital fold (p= 0.009), as well as the serum levels of fasting insulin (p= 0.04) and us-CRP (p= 0.002) were increased in obese
group.
Conclusions: These biomarkers may be helpful in the premature detection for obesity in children and could lead to early prevention of complications.