Eosinophilic Esophagitis: A Clinicopathological Review - Abstract
Eosinophilic esophagitis (EoE) is a chronic, atopic inflammatory disorder of the esophagus. With the escalating prevalence in children and young adults, revised guidelines have been established. Its pathogenesis has been associated with T helper Type 2 (Th2) inflammatory response. Diagnosis is based on a comprehensive evaluation including patient’s clinical manifestations and characteristic histologic findings on esophageal mucosal biopsies. The management of EoE involves dietary approaches and pharmacologic agents. This article provides a practical overview of recent literature pertaining to the epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE.