How Reliable are Urine Catecholamines in the Workup of Neuroblastoma Associated with Opsoclonus Myoclonus Ataxia? - Abstract
We report a rare case of neuroblastoma with Opsoclonus Myoclonus Ataxia (OMA)
and Horner’s syndrome in a previously healthy 17-month-old female who presented with titubations and a wide based gait. The patient had an initial negative workup including urine catecholamines. After further investigation, including a Magnetic Resonance Imaging (MRI) of the spine, neuroblastoma was revealed. This case emphasizes the importance of having a high suspicion for neuroblastoma despite negative urine catecholamine metabolites, especially when associated with OMA and Horner’s syndrome. Prompt treatment along with consultation with oncology is imperative to improve survival outcomes.