The Ladder of Cognition: Abstract Operations, Molecular Biology, Systems Science - Abstract
Bioinformatics of transition from signal to knowledge, experience and wisdom appears opaque. This transition has been described through four hierarchically nested specific operations to structurize the ladder of cognition. Cells could be classified according to their level in the cognitive ladder. The specific substrate proteins as required for desirable level of cellular cognition show a remarkable similar pattern in dynamical hierarchical structure in concurrence
with ontological ladders in informatics, mathematics, logic and linguistics. Within the cell, several factors together make the cognitive and decision-making system labyrinthine, where molecules respond to their intangible operators as the strings respond to the fingers of a sitar player. There emerges the broad outline of organization in the design of unified systems science. The outcomes have promises for pathology and molecular medicine, cell biology and synthetic biology, psychology and psychiatry, artificial intelligence and bio-robotics.