Naringenin (NRG) is a chemical found in citrus fruits like oranges and lemons, as well as in some other fruits like bergamot, tomatoes, cocoa, and cherries. It is a type of chemical called flavanones. NRG can help fight cancer, reduce swelling, and protect the body from harmful substances. Extensive research has been done over the past few decades, showing a detailed picture of many different plant chemicals and how they could be used for medical purposes. These natural compounds are important for medical use and are made up of polyphenols, followed by terpenoids and alkaloids. Many research studies have shown that phytochemicals play a key role in providing health benefits against different diseases. Not all plant chemicals have strong healing powers, and only some of them show important health effects. Naringenin is a compound in oranges and lemons that can make your immune system stronger, fix damaged DNA, and get rid of harmful molecules in your body. Although naringenin has limited availability in the body, it is known for its various healing properties, including reducing inflammation and acting as an antioxidant. This study looks at how naringenin can be helpful in treating important diseases because of its antioxidant properties.