Multiple Brain Abscess in a Patient with Community - Acquired Klebsiella Pneumoniae Invasive Syndrome - Abstract
Multiple brain abscesses is a life threatening condition, which challenges physicians clinical skills. We present a 65 years old man with a medical history of Type 2 Diabetes presented to ED with a history of 2 days of confusion and chest pain. The patient remained stable for a few days. After that he developed fever and his neurological status began to worsen. Abdomen CT revealed a liver abscess. CSF analysis matched for meningitis, brain MRI showed multiple focal images with a bilateral, supra and infratentorial distribution and restrictive intra-ventricular content interpreted as pyoventriculitis. Despite the thorough treatment with broad range antibiotics and drainage of the liver abscess, generalized infection persisted, leading to a septic shock and eventually his decease. Klebsiella Pneumoniae is a well known human pathogen. Extra-hepatic complications resulting from bacteraemic dissemination, including endophthalmitis, meningitis, necrotising fasciitis, and other illnesses, have also been recorded. K pneumoniae is known for being involved in Healthcare-Acquired infections but in the past few years it has become a source of acquired-community infections leading to a broad variety and eventually severe clinical presentation.