This review work tries to address on ethno botanical knowledge of Aloe plants in Ethiopia. There are 46 species of Aloe in Ethiopia in which about 66% of these Aloe species are endemic to the country. They are distributed in all floristic regions. Aloes are very important source of traditional medicine in Ethiopian communities to treat different ailments. In addition Aloes are used in soap production, jute sacks production, anti-microbial activities in cotton fabric, as thickening agent, degraded land rehabilitation and source of food for animals. Although there have been some attempts to conduct researches on Ethiopian Aloe species, the available information especially on commercial use, industrial use, propagation, germination and farming are insignificant and overlooked. As their distribution indicate Aloes are important component of Ethiopian dry-land ecosystem including pastoralist and agro-pastoralist area in which the amount of rain is low. In this area introducing Aloe farm system could be better alternative of poverty reduction and income generation. The presence of anthropogenic and environmental factors such as agricultural expansion into marginal lands, overgrazing, habitat destruction and restricted distribution may affect Aloe plants that could play great role in economic development for present and future generations of the country. As a result Aloe species need urgent conservation attention, effective documentation and further research.