Hypomagnesemia Associated with Caroli’s Disease - Abstract
Caroli’s disease is a hereditary disorder invariably associated with biochemical changes characteristic of cholestasis and/or chronic kidney disease (CKD).
Two cases of Caroli’s disease with CKD presented with hypomagnesemia. Urinary fractional excretion of magnesium was inappropriately high. Magnesium
mal-absorption and inappropriate urinary wasting are potential explanations of hypomagnesemia.
These case reports raise physician awareness about hypomagnesemia as one of the potential biochemical abnormalities that complicates the rare disorder
of Caroli’s disease and the possible appropriate course of treatment. They also attract investigators’ interest for more research to explore the exact cause of
this abnormality in this condition.