The Use of TREC Analysis as a Newborn Screening Test for Jacobsen Syndrome and T cell Deficiency - Abstract
Among the advances in medical detection of newborn disease, is the development of the T cell excision receptor circle or TREC assay. The use of the assay in the detection of Severe Combined Immunodeficiency (SCID) and T cell lymphopenia in newborn screening facilitates the detection of SCID early in life. TRECs may be used as surrogate markers for the production of newly formed T cells. To date, as of 2015, 26 states have implemented newborn screening utilizing TREC analysis.