Rheumatoid Arthritis (RA) typically begins with symptoms such as fatigue, stiffness, and musculoskeletal pain, which may take weeks to months to develop into joint involvement. Initially, the small joints are primarily affected, especially the small bones in the hands. Subsequently, larger joints become involved, leading to swelling, warmth, and pain. Morning stiffness or stiffness following periods of inactivity are indicative of active RA. Patients often report experiencing slowness or difficulty in movement when rising from bed or after remaining in a single position for an extended duration. This review is based on research studies indexed in Scopus, Science Direct, PubMed, and Google Scholar databases. Rheumatoid arthritis is an autoimmune inflammatory condition mainly distinguished by synovitis, which is often associated with the involvement of extra-articular organs, such as interstitial pneumonia. This condition also presents clinical symptoms that include pain, swelling, stiffness in multiple joints, fever, and malaise.