Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Presenting with Brain Metastases - Abstract
Diffuse Sclerosing Variant of Papillary Carcinoma of the thyroid (DSVPC) is a rare variant of Papillary Thyroid Cancer (PTC). It is characterized by diffuse involvement of one or both thyroid lobes, with dense fibrosis, squamous metaplasia, and lymphocytic infiltration. It has more aggressive course, and higher rate of metastasis compared to the conventional PTC. We describe a female with DSVPC who presented with hemorrhagic brain metastasis, and pulmonary metastasis.