Craniosynostoses are very severe genetic conditions, they compromise not only the physical functions but also mental well-being of an affected person, because this abnormality cannot be masked - it is on patient`s cranium and face. Research in the field of craniofacial genetics opens new horizons in craniofacial medicine. DNA testing allows connecting a specific mutation with a particular phenotype, and this can help in predicting the development of craniofacial complex, as well as in planning surgery, post-operative treatment, and genetic counselling of the patient.