Objective: The aim of this study is to determine the change in emotion regulation skills of children with autism spectrum disorder due to the pandemic period as well as the interruption of their rehabilitation services. Method: Parents of 40 children with autism spectrum disorder aged 3-18 (with a mean age of 11.6), who discontinued their rehabilitation services due to the pandemic, completed the Emotion Regulation Checklist in April and September 2020 via Google form. Results: The emotion regulation skills including emotion regulation (Z= -2.758; p= 0.006) and lability/negativity (Z= -3.355; p= 0.001) of children with autism spectrum disorder decreased significantly during the pandemic period. Conclusion: This study provided the first evidence that children with autism spectrum disorder need support to adapt to routine life in the current pandemic conditions. In order for children with autism spectrum disorder to adapt to the challenges brought by the pandemic, health professionals need to develop and implement the necessary intervention plans that include improving their emotion regulation skills.