Most providers are supportive of women having access to safe and effective birth control options. However, before any woman starts a birth control regimen, it is important for them to understand all the risks and ramifications. The newly FDA-approved over-the-counter mini-pill (the Opill), is one such option, and patients should understand that taking this pill is not without considerable medical consequences. And these consequences can adversely affect a woman’s quality of life and put her at risk for many chronic medical illnesses [1].