Background: Despite of access data on influence of gynecological pathologies on development of sexual dysfunctions, there is no clear scientifically proved evidence on influence of sexual disorders, such as anorgasmia, on development of gynecological pathologies. Objective: Objective of study was detection of relationship between women’s sexual functions (orgasm and libido) and gynecological pathologies. Materials and methods: 676 sexually active women (aged 18-55yy, mean age 31, 7+3) have been investigated on the basis of Center for Reproductive Medicine “Universe” and outpatient clinics of Medical Corporation Evex. They were divided in 3 groups:I gr. – 148 women with ovarico-varicocele (OVVC), II gr. – 125 women with dilatation of myometrium veins (DMV) and III gr. - 403 women with other gynecological pathologies (myoma, inflammatory diseases, gynecological-endocrine disorders, etc.). In all groups frequency of orgasms (never, rare, often, always) and grade of libido (low, medium, high) have been assessed by interviewing. Results: In I group rate of women with anorgasmia (70,9%) and rare orgasms (20,9%) was significantly higher (P<0.01) than rate women, who had orgasms often (6,1%) or always (2,0%). In II group rate of women with anorgasmia (39,2%) and rare orgasms (44,0%) was significantly higher (P<0.01) than women, who had orgasms often (12,8%) or always (4,0%). In III group generally was observed prevalence of women without absolute absence or presence of orgasms -rate of women, who had orgasms often (36,7%) or rarely (44,4%) was significantly higher (P<0.01) than women, who had orgasm always (5,2%) or never (13,6%). As of relationship between intensity of sexual drive (libido) and frequency of orgasms – in all groups there was inverse dependence - women with anorgasmia and rare frequency of orgasms mainly had low or medium libido and in women, who had orgasms often or always libido was mainly medium or high. Conclusion: Orgasmic dysfunctions (anorgasmy) can promote congestive process in pelvis, development of varicosis of ovarian and pelvic veins (with corresponding other gynecological complications), which themselves can determine chronic pelvic pain that deepens the anorgasmic process. In younger ages and early stages of beginning of sexual life, timely management of anorgasmy might be good prevention for further development of gynecological pathologies. The issue needs further investigation for revealing of cause-result relationship.