The Effects of Exposure to Weather and Climate Variations on Human Semen Parameters: A Retrospective Cohort Study of Fertile Men Living in Different Altitudes of China - Abstract
Purpose: To estimate associations of weather and climate variation exposures with semen parameters. Methods: We retrospective evaluated the associations of weather, climate and altitude variation with semen parameters of fertile male living in China from 2018 to 2021. All the weather and climate parameters were obtained from The National Meteorological Science Data Centre of China. Results: The outcomes of exposure were evaluated by semen analysis, including sperm donors and healthy males. For the short-term exposure to daily weather fluctuations, the non-parameter spearman-test results only revealed the progressive motility (%) was correlation with all the weather factors, including pressure (?=-0.111, p= 0.000), temperature (?=0.076, p= 0.000) and moisture (?=0.046, p= 0.003). For the long-term exposure to climate, the Tibetan population living in the Qinghai Tibet Plateau showed superior concentration of semen (median=63.20 million/ml, p=0.000) and the males living in the Turpan Basin exhibited superior volume of semen (median=3.55ml, p=0.000) than others. Furthermore, combined all the climate and altitude factor, the generalized linear model between the climate variations and dependent variable semen parameters showed that the oxygen content (%) of different altitudes had significantly effects on all the seme parameters, especially on the volume (95% CI, 0.612-2.170, p= 0.000) . Conclusions: The data of fertile men living in different altitudes of china showed the semen parameters are sensitive to the temperature of the daily weather fluctuation, while the oxygen content were the most sensitive parameters