Rabies Virus Related to Vampire Bats (Desmodus rotundus) Isolated from a Crab-Eating Fox (Cerdocyon thous) in Southeast Brazil - Abstract
In this study, rabies virus was isolated from a naturally infected crab-eating fox [Cerdocyon thous] in a rural area of São Paulo State, Brazil. The sample was positive for the standard techniques used for rabies diagnosis. The isolate was antigenically characterized using anti-nucleoprotein monoclonal antibodies. Studies on molecular epidemiology by patterns of nucleotide substitution in the nucleoprotein gene showed that the isolate was genetically homologous to the rabies variant maintained and transmitted by the common vampire bat Desmodus rotundus. This is the first report of detection of this variant from a crab-eating fox in Brazil and represents evidence of cross-species transmission. This was the unique report where this variant was isolated from a crab eating fox in Brazil.